Using bidirectional chemical exchange for improved hyperpolarized [13 C]bicarbonate pH imaging.

CONCLUSION: The novel multi-EPI pulse sequence can boost CO2 imaging signal in hyperpolarized 13 C bicarbonate imaging while introducing minimal pH bias, helping to surmount a major hurdle in hyperpolarized pH imaging.
PMID: 31050049 [PubMed - as supplied by publisher]

Source: Magnetic Resonance in Medicine - May 2, 2019 Category: Radiology Authors: Korenchan DE, Gordon JW, Subramaniam S, Sriram R, Baligand C, VanCriekinge M, Bok R, Vigneron DB, Wilson DM, Larson PEZ, Kurhanewicz J, Flavell RR Tags: Magn Reson Med Source Type: research