Myeloid leukemia with high EVI1 expression is sensitive to 5-aza-2 ′-deoxycytidine by targeting miR-9

ConclusionsOur results suggest that EVI1 may be involved in leukemia cell proliferation and apoptosis via the regulation of miR-9 promoter methylation. 5-AZA may represent a promising therapeutic option for EVI1-high leukemia patients.
Source: Clinical and Translational Oncology - Category: Cancer & Oncology Source Type: research