Costunolide Inhibits the Growth of OAW42-A Multidrug-Resistant Human Ovarian Cancer Cells by Activating Apoptotic and Autophagic Pathways, Production of Reactive Oxygen Species (ROS), Cleaved Caspase-3 and Cleaved Caspase-9.

CONCLUSIONS Costunolide inhibited growth, apoptosis, ROS generation, and was associated with loss of mitochondrial membrane potential of OAW42-A multidrug-resistant ovarian cancer cells. PMID: 31043579 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31043579?dopt=Abstract

Source: Medical Science Monitor - May 4, 2019 Category: Research Tags: Med Sci Monit Source Type: research