Gefitinib-coated balloon inhibits the excessive hyperplasia of intima after vascular injuries through PI3K/AKT pathway.

CONCLUSIONS: Gefitinib-coated balloons were able to suppress the excessive proliferation in the common carotid arterial intima of rats more effectively than the paclitaxel-coated ones. The underlying mechanism may cover the PI3K/AKT signal pathway.
PMID: 31045551 [PubMed - as supplied by publisher]

Source: Technology and Health Care - April 29, 2019 Category: Medical Devices Authors: Tang F, Liu M, Zeng O, Tan W, Long J, Liu S, Yang J, Chu C Tags: Technol Health Care Source Type: research