Anal sphincter botulinum toxin injection in children with functional anorectal and colonic disorders: A large institutional study and review of the literature focusing on complications

Botulinum toxin (botox) is a commonly used treatment for functional anorectal and colonic disorders. Although generally regarded as safe, complications associated with botox injection into the anal sphincters in children with severe defecation disorders are not well described. We aimed to review our institutional experience and the existing literature to better understand the safety of this practice.

Source: Journal of Pediatric Surgery - May 2, 2019 Category: Surgery Authors: Devin R. Halleran, Peter L. Lu, Hira Ahmad, Michela M. Paradiso, Haley Lehmkuhl, Allison Akers, Alexandra Hallagan, Neetu Bali, Karla Vaz, Desalegn Yacob, Carlo Di Lorenzo, Marc A. Levitt, Richard J. Wood Source Type: research