Right atrial –right ventricular coupling in heart failure with preserved ejection fraction

ConclusionIn compensated HFpEF patients RV early filling was impaired and compensated by increased RA booster pump function, while RV systolic function was preserved. Impaired RV diastology and RA –RV interaction were linked to impaired exercise tolerance and RA–RV-coupling seems to be independent of RV relaxation, suggestive of an independent pathophysiological contribution of RA dysfunction in HFpEF.Clinical-Trial-RegistrationNCT02459626 (www.clinicaltrials.gov).
Source: Clinical Research in Cardiology - Category: Cardiology Source Type: research