The Impact of Unpredictability on Dyspnea Perception, Anxiety and Interoceptive Error Processing

Conclusion Taken together, the present study demonstrated that unpredictability of upcoming dyspnea increases the perception of dyspnea, especially its affective unpleasantness. Moreover, this effect seems related to increased state and trait anxiety and interoceptive error processing, especially when the occurrence of dyspnea is particularly unpredictable such as in early experimental phases. Future studies are required to further substantiate these findings in patients suffering from dyspnea. Data Availability This study does not include any clinical dataset to be shared. The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Ethics Statement This study was carried out in accordance with the recommendations of the Social and Societal Ethics Committee of the University of Leuven with written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocol was approved by the Social and Societal Ethics Committee of KU Leuven (G-2018-02-1123). Author Contributions AvL, OVdB, and YT contributed to the conception and design of the study. AvL and YT contributed to the collection, analysis, and interpretation of the data. AvL and YT wrote the manuscript with critical input from JQ and OVdB. All authors read and approved the final version of the manuscript. Funding This work was supported by grants from the Research Fund KU Leuve...
Source: Frontiers in Physiology - Category: Physiology Source Type: research