Chronic kidney disease puzzle highlighted at Costa Rica workshop
Researchers from around the world shared insights into chronic kidney disease of unknown origin in agricultural communities. (read more)
Publication date: 15 September 2020Source: Life Sciences, Volume 257Author(s): Beatriz M.V. Pereira, Karina Thieme, Larissa de Araújo, Alice C. Rodrigues
In conclusion, sitting for prolonged periods of time without interruption is unfavorably associated with DBP and HDL cholesterol. Exercise Slows Inappropriate Growth of Blood Vessels in a Mouse Model of Macular Degeneration https://www.fightaging.org/archives/2020/07/exercise-slows-inappropriate-growth-of-blood-vessels-in-a-mouse-model-of-macular-degeneration/ Excessive growth of blood vessels beneath the retina is a proximate cause of blindness in conditions such as macular degeneration. Researchers here provide evidence for physical activity to be influential in the pace at which this process of tissue...
We report a 30-year-old female patient with diabetes who has acromegaloid features, prominent umbilicus, prominent muscles, prominent subcutaneous veins, and gross hepatomegaly. Near-total loss of subcutaneous fat was confirmed by whole-body magnetic resonance imaging and laboratory data revealed significant hypertriglyceridemia, uncontrolled diabetes mellitus, and heavy proteinuria with stage IIIa chronic kidney disease. Her blood film revealed thrombocytosis that on further evaluation by bone marrow biopsy was confirmed to be a myeloproliferative neoplasm (MPN); essential thrombocytosis (ET). She also had skin lesions th...
Publication date: Available online 10 July 2020Source: IRBMAuthor(s): N. Bhaskar, S. M
Publication date: September 2020Source: Biomedical Signal Processing and Control, Volume 62Author(s): Bhaskar Navaneeth, M Suchetha
Publication date: November 2020Source: Microvascular Research, Volume 132Author(s): Chengsheng Li, Xiaoyi Zhong, Wenyu Xia, Jin He, Hua Gan, HongFei Zhao, Yunfeng Xia
Cystatin C is a well-validated marker of glomerular filtration rate in chronic kidney disease. Higher plasma concentrations of cystatin C are associated with worse clinical outcomes in heterogenous populations...
ConclusionsCKD due to T2DM had been the main contributor to the increasing burden of CKD over the past several decades. We suggest a more ‐pragmatic approach focusing on early diagnosis, primary care, and adequate follow‐up to reduce mortality and the long‐term burden in low to middle SDI regions. Interventions should address high systolic blood pressure as well as overweight and obesity problems, especially in high‐income reg ions.
Atrial fibrillation (AF) is strongly linked to chronic kidney disease (CKD) and both of these conditions contribute to poor cardiovascular outcomes. We evaluated the impact of renal failure on major adverse cardiovascular events (MACE) in AF, and predictive value of the 2MACE score in this post-hoc analysis of the AMADEUS trial. The primary endpoint was MACE (composite of myocardial infarction, cardiac revascularisation and cardiovascular mortality). Secondary endpoints included the composite of stroke, major bleeding and non-cardiovascular mortality, and each of the specific outcomes separately.
This study revealed that the risk factors for the death in these elderly patients included comorbidities, increased levels of C-reactive protein and blood urea nitrogen, and lymphopenia during hospitalization. PMID: 32651993 [PubMed - as supplied by publisher]