Further support linking the 22q11.2 microduplication to an increased risk of bladder exstrophy and highlighting LZTR1 as a candidate gene

ConclusionOur study further emphasizes the involvement of the 22q11.2 region in BEEC development and highlightsLZTR1 as a candidate gene underlying the urogenital malformation.

Source: Molecular Genetics & Genomic Medicine - April 30, 2019 Category: Genetics & Stem Cells Authors: Johanna Lundin, Ellen Markljung, Izabella Baranowska K örberg, Wolfgang Hofmeister, Jia Cao, Daniel Nilsson, Gundela Holmdahl, Gillian Barker, Magnus Anderberg, Vladana Vukojević, Anna Lindstrand, Agneta Nordenskjöld Tags: ORIGINAL ARTICLE Source Type: research