Diagnostic utility of transbronchial lung cryobiopsy: Two cases of anti-aminoacyl-tRNA synthetase syndrome with respiratory failure

Publication date: Available online 1 May 2019Source: Respiratory InvestigationAuthor(s): Hanako Yoshimura, Nobuyasu Awano, Minoru Inomata, Naoyuki Kuse, Mari Tone, Tatsunori Jo, Tamiko Takemura, Toshio Kumasaka, Takehiro IzumoAbstractTransbronchial lung cryobiopsy (TBLC) is a useful and safe method for the diagnosis of interstitial lung disease (ILD). Herein, we describe the cases of two patients who developed ILD from anti-aminoacyl-tRNA synthetase syndrome with respiratory failure. TBLC was performed instead of surgical lung biopsy. There were no complications, and sufficient specimens were harvested to make the precise histopathological diagnosis. TBLC should be considered as a critical approach for the histopathological diagnosis of ILD in patients who cannot undergo surgical lung biopsy because of respiratory failure.
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research