Actinomycotic osteomyelitis of a long bone in an immunocompetent adult: a case report and literature review

Actinomycosis is a rare, chronic granulomatous disease caused by Gram-positive anaerobic bacteria that colonize the oral cavity. Cervicofacial actinomycosis is the most frequent clinical presentation of actino...
Source: BMC Musculoskeletal Disorders - Category: Orthopaedics Authors: Tags: Case report Source Type: research

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CONCLUSIONS:: Cervicofacial actinomycosis involves soft tissue surrounding the facial skeleton and oral cavity and is typically associated with a history of mucosal trauma, surgery, or immunodeficiency. The patient was appropriately treated but experienced disease progression and escalation of therapy. Although actinomycosis is typically not an aggressive bacterial infection, this case illustrates the need for prompt recognition of persistent disease and earlier surgical intervention in cases of recalcitrant cervicofacial actinomycosis. Chronic actinomycosis has the potential for significant morbidity. PMID: 30371104 ...
Source: The Annals of Otology, Rhinology, and Laryngology - Category: ENT & OMF Authors: Tags: Ann Otol Rhinol Laryngol Source Type: research
Actinomycosis is a rare, chronic, slowly progressive granulomatous disease caused by filamentous, gram-positive, anaerobic bacteria from the Actinomycetaceae family (genus Actinomyces). Of late, it has become a rare condition because of the widespread use of antibiotics. When clinical symptoms are not typical, diagnosis of this condition becomes difficult. Here, we report a case involving an 82-year-old woman who was diagnosed with actinomycotic osteomyelitis of the mandible using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: Case Report Source Type: research
Introduction: Actinomycosis is a rare soft tissue infection which seldom involves the bone. Actinomycotic Osteomyelitis, particularly affecting the cervicofacial region, is scarcely reported in the adult population.
Source: The British Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Tags: P82 Source Type: research
This report presents two cases of maxillary and two cases of mandibular actinomycosis osteomyelitis, with the diagnosis particularly based on histological procedures. The highly diversified pathogenicity of the phenomenon and the absence of solid diagnostic criteria are discussed. Laboratory challenges are emphasized, and a comprehensive overview of the entity including treatment alternatives is given along with a review of the relevant literature.
Source: Journal of Dental Sciences - Category: Dentistry Source Type: research
Introduction: Actinomycosis is a subacute to chronic infection caused by a group of anaerobic or microaerophilic filamentous bacteria, the Actinomyces species. It is characterized by granulomatous inflammation, contiguous spreading to adjacent tissues, and consequently purulent abscesses and sinus formation. Cervicofacial actinomycosis represents two thirds of these infections with the mandible being the most common location. Bone involvement such as osteomyelitis is relatively rare, and is found in 10% of all cervicofacial cases.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
We conducted a review of 14 patients with an established histological diagnosis of Ewing's sarcoma in order to analyze the clinical and radiological features of the disease as observed at King Khalid University Hospital and to compare them with those reported in the literature. There were 9 males and 5 females, and the average age was 11 years. All patients but one complained of a painful swelling. Symptoms had lasted an average of 4 months and 50% of the patients had a history of trauma. The radiological appearance varied according to the bone and the part of the bone involved. Only 36% of the patients exhibited the class...
Source: Annals of Saudi Medicine - Category: Journals (General) Tags: ISSUE 2 Source Type: research
We report here a rare case of Actinomyces-associated calcifications around an impacted third molar of the mandible. A 76-year-old man with left mandibular pericoronitis was referred to our department. A panoramic radiograph showed alveolar bone resorption caused by severe periodontitis of the left mandibular second molar and multiple small radiopaque spots around the crown of left mandibular third molar in a radiolucent lesion. Computed tomography revealed that the lesion of the left mandibular retromolar lesion was low density, with multiple high density spots surrounding the third molar crown surface. Removal of the lesi...
Source: Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology - Category: ENT & OMF Source Type: research
Abstract: Actinomycosis is an infection of filamentous, gram-positive anaerobic bacteria. Actinomycosis of jaw bone is rare and the diagnosis is often difficult. The aim of this patient report is to present an actinomycotic osteomyelitis of mandible in a 30-year-old male patient. The patient presented with a chief complaint of pain and unhealed dental socket after mandibular teeth extractions. Radiographs showed ill-defined radiolucencies and perforation of buccal and lingual cortical plate; several biopsies and different therapy could not improve the lesion because of fault diagnosis and improper treatment. Finally, the a...
Source: Journal of Craniofacial Surgery - Category: Surgery Tags: Brief Clinical Studies Source Type: research
We describe a case of progressive, significant, bony destruction of right midface over approximately 27 months from an unknown aetiology. A 58‐year‐old male patient originally presented with a white lesion in the upper right buccal sulcus, which a biopsy confirmed to be a benign hyperplastic inflammatory lesion. However, 16 months later, the patient returned with signs and symptoms suspicious of a malignant aetiology. A series of computed tomography scans over 27‐month period revealed progression of extensive permeative right midfacial bony destruction now with intracranial involvement. Contrary to the clinical and r...
Source: Oral Surgery - Category: ENT & OMF Authors: Tags: Case Report Source Type: research
Actinomycosis is a slowly progressing infection caused by Actinomyces species, which are gram-positive anaerobic bacillus. Actinomyces osteomyelitis is a rare condition in head and neck, often occurs after tooth extraction and trauma or surgery in jaw.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
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