Timing of Antenatal Corticosteroid Administration in Monoamniotic Twins
Conclusion Administration of ACS on admission is not effective. Fetal heart rate tracing surveillance might be a better methodology to predict delivery and guide ACS administration. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | open access Full text
A 41-year-old Congolese woman born in 1977 presented in February 2018 to our emergency department with severe abdominal pain. Her medical history was notable for idiopathic collapsing glomerulopathy for which she was being initially treated with corticosteroids, later switched to tacrolimus. Additionally she was on candesartan 16 mg/d, then later switched in 2014 to enalapril 20 mg/d. During 2017, she was poorly compliant with her medications. In February 2018, her medications included tacrolimus, furosemide, spironolactone, lercanidipine, and enalapril.
Publication date: Available online 20 August 2019Source: IDCasesAuthor(s): Takahiro Karasuno, Hiroshi Sata, Yuri Noda, Masami Imakita, Masato YasumiAbstractInvasive candidiasis remains an important cause of mortality and morbidity in patients with underlying diseases. Here, we report a case of gastric perforation due to Candia glabrata infection in a 74-year-old-male with Paroxysmal nocturnal hemoglobinuria (PNH) who received long-term corticosteroid treatment of hemophagocytic syndrome associated with acute cholecystitis. Total gastrectomy was performed, and he was treated liposomal amphotericin B. The patient was extubat...
Background: Azathioprine (AZA) and mycophenolate mofetil (MMF) are the first-line adjuvant immunosuppressant used in combination to corticosteroids for pemphigus vulgaris (PV) and pemphigus foliaceus (PF). However, few studies have compared the efficacy between AZA and MMF for pemphigus especially in the Asian population.
Background: Patients with pemphigus (PEM) and bullous pemphigoid (BP) have risk factors for decreased bone mineral density including long-term use of systemic corticosteroids and chronic inflammation. Few studies examined the associations of PEM and BP with osteoporosis and fractures. We sought to determine whether PEM and BP are associated with osteoporosis and fracture in the US population.
This study aimed to elucidate and compare such effects in a human Th17 skin inflammation model.
Atopic dermatitis (AD) is the most common chronic pediatric skin disease, affecting an estimated 13% of children in the United States. Because access to specialized care is limited, and poorly controlled disease is marked by interval flares, many of these patients seek treatment in the emergency department (ED). In this setting, management often includes oral corticosteroids, antihistamines and antibiotics, an approach that provides short-term relief, but can potentiate rebound flares. The ED setting also carries several challenges related to lack of well-defined guidelines for managing flares, criteria for hospitalization...
Background: Psoriasis is a chronic, immune-mediated disease that varies widely in its clinical expression. Topical corticosteroids (TCS) are the mainstay of treatment. Long-term safety remains a concern, limiting use, and posttreatment flare common. Tazarotene has also been shown to be effective in psoriasis, with efficacy maintained several weeks posttreatment. Fixed combination therapy with TCS may improve psoriasis signs and may maintain a therapeutic effect while minimizing posttreatment flare or rebound
Background: Topical corticosteroids may lose efficacy over time. Poor treatment outcomes may be due to poor adherence. We evaluated how frequently patients with psoriasis resistant to topical treatment respond to topical corticosteroids
Background: Psoriasis (PsO) is often treated with topical and oral corticosteroids, topical noncorticosteroids, phototherapy/PUVA or nonbiologic systemic medications. Ixekizumab (IXE), a high-affinity monoclonal antibody that selectively targets IL-17A, is used for the treatment of moderate-to-severe PsO. In this analysis, we evaluated the treatment patterns of concomitant medications in patients (pts) with PsO who switched from any previous medications to IXE.
Alitretinoin is a first generation retinoid indicated for moderate to severe chronic hand eczema (CHE) resistant to topical steroid therapy. The efficacy and safety of oral alitretinoin in Asian patients with CHE has rarely been studied. The aim of this study was to evaluate the efficacy and safety of oral alitretinoin in the treatment of CHE in Korean patients under daily real life, which admitted concomitant use of topical corticosteroids. We performed a retrospective study of 107 Korean patients diagnosed as CHE.