Detection Study of Bipolar Depression Through the Application of a Model-Based Algorithm in Terms of Clinical Feature and Peripheral Biomarkers
Conclusion: It seems to be feasible to combine different types of clinical characteristics with biomarkers in order to detect bipolarity of all depressive episodes. Neurotrophic factors of our interest presented its stable discriminant potentiality in unipolar and bipolar depression, deserving validation analysis in larger samples.IntroductionThe Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) separates the mood disorders into two sections: depressive and related disorders, and bipolar and related disorders. The new version of the diagnostic manual of bipolar disorders emphasizes more specific manifestations related to hypomanic and mixed manic states, which are considered to be a separate class of mood disorder “in terms of symptomatology, family history and genetics” (1–3). From a statistical point of view, the nature of the diagnostic classification of depressive disorder can be clearly taken as a typical dichotomous problem with only two possible outcomes: one is bipolar depressive disorder (BPD) and the other is major depressive disorder (MDD).In spite of its clear-cut division in diagnostic manual, a definite diagnosis for bipolar disorder remains an elusive goal. In a 10-year follow-up study of 290 unipolar depressed patients, Holmskov et al. have reported that the overall risk of conversion from initial diagnosis of unipolar depression to later bipolar disorder reaches up to 20.7% (4). The major challenge for clinical dec...
Publication date: Available online 4 April 2020Source: Radiation Physics and ChemistryAuthor(s): R.S. Omar, S. Hashim, S.K. Ghoshal, D.A. Bradley, N.D. Shariff
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Taoiseach will work one shift a week; Italy reports lowest increase in deaths in two weeks; Spain records smallest rate of increase in infectionsLatest developments: at a glanceUK coronavirus – latestSweden prepares for possible tighter measuresSpanish PM: survival of EU rests on response to crisisSee all of our coronavirus coverage7.45pmBSTGreek authorities have placed Mykonos and Santorini – two of the country’s most popular isles - under night curfew, announcing that residents will be unable to leave their homes between 8 PM and 8AM. Further restrictions on movement were also unveiled Sunday after a se...
In conclusion, this study suggests that the self-administration of a cosmetic cream enriched with essential oils should be considered as a stress resilience fostering strategy due to its favorable physiological, neuroendocrine and psychological effects. PMID: 32241205 [PubMed - as supplied by publisher]
The chemist wants the Gates Foundation –backed institute to share its expertise during the coronavirus pandemic and advocate for public health
Jerome Adams reaches for second world war imageryNo White House briefing as president tweets insteadCoronavirus – US updatesCoronavirus – global updatesSee all our coronavirus coverageThe US surgeon general warned the country on Sunday that it will face a “Pearl Harbor moment” in the next week, with an unprecedented numbers of coronavirus deaths expected coast to coast.Related:Jared Kushner and his shadow corona unit: what is Trump's son-in-law up to?Continue reading...
I was offered an out of match fellowship position and accepted it 2 days ago. Now, due to family issues It would not be ideal for me to relocate to that area. Is there a way I can withdraw my acceptance (I haven’t sign the intent letter or anything whatsoever, just email agreement) or would it be profesional suicide?
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