Inherited predisposition to malignant mesothelioma and overall survival following platinum chemotherapy [Medical Sciences]

Survival from malignant mesothelioma, particularly pleural mesothelioma, is very poor. For patients with breast, ovarian, or prostate cancers, overall survival is associated with increased sensitivity to platinum chemotherapy due to loss-of-function mutations in DNA repair genes. The goal of this project was to evaluate, in patients with malignant mesothelioma, the...

Source: Proceedings of the National Academy of Sciences - April 29, 2019 Category: Science Authors: Raffit Hassan, Betsy Morrow, Anish Thomas, Tom Walsh, Ming K. Lee, Suleyman Gulsuner, Meghana Gadiraju, Vasiliki Panou, Shaojian Gao, Idrees Mian, Javed Khan, Mark Raffeld, Snehal Patel, Liqiang Xi, Jun S. Wei, Mary Hesdorffer, Jingli Zhang, Kathleen Calz Tags: Biological Sciences Source Type: research