Elevated NLR May Be a Feature of Pediatric Brain Cancer Patients
In this study we investigated NLR and LMR in pediatric brain cancer patients on day of diagnosis before any treatment administration.
Methods
Clinical data from pediatric brain cancer patients (M = malignant group) and elective pediatric patients hospitalized for hernia repair were retrospectively analyzed. Exclusion criteria were steroid treatment before the blood test and a history of concomitant diseases. Age, Sex, treatment, blood count plus differential were collected from blood tests performed before surgery in both groups. NLR, and the LMR were calculated and significance was determined by paired T-test. p < 0.05 was considered as statistically significant. ANOVA test was used to compare mean of NLR value in different brain tumor types.
Results
Clinical data from 120 pediatric brain cancer patients and 171 elective pediatric patients hospitalized for hernia repair were retrospectively analyzed. The study was approved by the ethical review boards of both Sheba and Tel Aviv Sourasky Medical Centers and was consistent with the declaration of Helsinki. Cancer patients who received dexacort before the blood test were excluded. Children from the elective hernia surgery control group with known background diseases were also excluded. Ninety-nine cancer and 62 control patients that met the inclusion criteria and had all the data in the medical records were included in the analysis. Brain cancer patients consisted of 37 astrocytoma patients, 27 medulloblastoma patie...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
More News: Academia | Adenocarcinoma | Adenoviruses | Allergy & Immunology | Astrocytoma | Bladder Cancer | Brain | Brain Cancers | Brain Tumor | Breast Cancer | Breast Carcinoma | Canada Health | Cancer | Cancer & Oncology | Cancer Therapy | Cancer Vaccines | Carcinoma | Chemotherapy | Child Development | Children | Clinical Trials | Colon Cancer | Colorectal Cancer | Environmental Health | Epithelial Cancer | Gastric (Stomach) Cancer | Gastroenterology | Gastroschisis Repair | Glioma | Head and Neck Cancer | Hematology | Hepatocellular Carcinoma | Hernia Repair | Hospitals | Immunotherapy | Israel Health | Italy Health | Liver | Liver Cancer | Lung Cancer | Medical Ethics | Medulloblastoma | Melanoma | Middle East Health | Neoadjuvant Chemotherapy Therapy | Neoadjuvant Therapy | Neurology | Neurosurgery | Non-Small Cell Lung Cancer | Nutrition | Orthopaedics | Ovarian Cancer | Ovaries | Pancreas | Pancreatic Cancer | Pediatric Hernia | Pediatric Hernia Repair | Pediatrics | Pilocytic Astrocytoma | Reproduction Medicine | Sarcomas | Skin Cancer | Squamous Cell Carcinoma | Statistics | Study | Urology & Nephrology | USA Health | Vaccines | Wales Health