Long non-coding RNA Linc00221 mediates cisplatin resistance in non-small-cell lung cancer (NSCLC) via sponging miR-519a.

In conclusion, Linc00221 promotes cisplatin resistance in NSCLC through the downstream miR-519a/ZBTB5 signaling axis, which could be used as a potential diagnostic and therapeutic target for clinical cisplatin-resistant NSCLC patients.
PMID: 31029744 [PubMed - as supplied by publisher]

Source: Biochimie - April 24, 2019 Category: Biochemistry Authors: Tang H, Han X, Li M, Li T, Hao Y Tags: Biochimie Source Type: research