Central Inhibition of Tumor Necrosis Factor Alpha Reduces Hypertension by Attenuating Oxidative Stress in the Rostral Ventrolateral Medulla in Renovascular Hypertensive Rats

In this study, spontaneous baroreflex sensitivity (SBRS) was also calculated through the sequence method by the computer software CardioSeries (v2.4). A baroreflex sequence was defined as a sequence of at least four heart beats in which both systolic arterial pressure and pulse interval increased (up sequences) or decreased (down sequences) as previously described (Braga et al., 2008). Evaluation of Sympathetic Tonus to the Vasculature In a separate group of rats, the sympathetic vascular tone was evaluated by an intravenous injection of hexamethonium (30 mg/Kg, Sigma-Aldrich, São Paulo, Brazil), a ganglionic blocker. The magnitude of the fall in blood pressure yield the contribution of the sympathetic tone to sustain blood pressure at baseline level. Power Spectral Analysis of Systolic Arterial Pressure Systolic arterial pressure (SAP) signals were evaluated by power spectral analysis. In our study, we were particularly interested in the low-frequency component of SAP signals (LF, 0.25–0.8 Hz), that is representative of the modulatory effects of sympathetic tone and was reported to take origin from the RVLM (Kuo et al., 1997). To reach this goal, beat-by-beat time series of SAP were extracted from baseline cardiovascular recordings (10 min epochs) of pulsatile arterial pressure of rats in each group and the variability of these series was assessed using Fast Fourier Transform spectral analysis (Cardioseries Software v2.4) (Tezini et al., 2013). Measurement ...
Source: Frontiers in Physiology - Category: Physiology Source Type: research

Related Links:

Publication date: Available online 18 January 2020Source: The American Journal of SurgeryAuthor(s): Asishana A. Osho, Muath M. Bishawi, Elbert E. Heng, Ejiro Orubu, Aaron Amardey-Wellington, Mauricio A. Villavicencio, Masaki FunamotoAbstractBackgroundFailure to Rescue (FTR) is a valuable surgical quality improvement metric. The aim of this study is to assess the relationship between center volume and FTR following lung transplantation.MethodsUsing the database of the United Network for Organ Sharing (UNOS) all adult, primary, isolated lung recipients in the United States between May 2005 and March 2016 were identified. FTR...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Awaken Joy, LLC, Psychiatric Nurse Practitioner, Fairbanks, AK, 99709 | Psychology Today Awaken Joy, LLC, Psychiatric Nurse Practitioner, Fairbanks, AK, 99709, Thank you for your interest. Susana ("Sana") Donofry is a psychiatric nurse practitioner. She prescribes medicine for ADHD and mental health issues like depression, anxiety, and addiction. She accepts most insurance plans... www.psychologytoday.com I was looking at psych profiles in the 20 or so states that allow nurse practitioners to practice independently, it was surprising to s...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Psychiatry Source Type: forums
Authors: Lin WC, Tsai JP, Lai YH, Lin YL, Kuo CH, Wang CH, Hsu BG Abstract Osteoprotegerin (OPG) is a potential biomarker of cardiovascular disease complications and severity. Peripheral arterial disease (PAD) is associated with an increased risk of death in patients on peritoneal dialysis (PD). Therefore, this study aimed to evaluate the relationship between serum OPG levels and PAD by measuring the ankle-brachial index (ABI) of patients on PD. A commercial enzyme-linked immunosorbent assay kit was used to measure OPG values. Left or right ABI values of
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
CONCLUSION: Psychiatric services might consider different priorities referring to work and life and their impact on coping with depression among men. PMID: 31952090 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSIONS: The GSDS-26 is a preliminary validated multidimensional scale for better identifying depression in men and may be suitable for routine use after further validation. PMID: 31952089 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSIONS: Our results stress the relevance of increases in depressive symptoms for upcoming functional decline among the oldest old. Further longitudinal studies are required to replicate our findings. PMID: 31952087 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSION: Shame needs to be viewed in context of gender roles, status, and their interaction. Future studies should investigate the influence of mental health literacy. PMID: 31952086 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
CONCLUSIONS: In the population studied mental illness alone was not a sufficient predictor for suicide. Rather, an interaction between mental illness, psychosocial crisis and other factors may explain and predict suicides. Suicide prevention should better address the needs of relatives and family doctors and offer specific low-threshold services. PMID: 31952085 [PubMed - as supplied by publisher]
Source: Psychiatrische Praxis - Category: Psychiatry Tags: Psychiatr Prax Source Type: research
The objective of the study is to describe the prognostic factors that would allow maintaining functionality at 12 months.MethodFrom June 1, 2010 to May 31, 2013, all patients older than 69 years with hip fracture due to bone fragility admitted to the Geriatric Acute Unit of our hospital were included. We define as functional maintenance those patients who have lost between 0 and 15 points in the Barthel Index with respect to the previous to the fracture. Prospective study of bivariate data analysis for related and multivariate prognostic factors for predictive predictors.Results271 patients were included, of them, 146 (54....
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
ConclusionsUnplanned admissions are more frequently related to general anaesthesia, lengthy surgeries and procedures such as arthroscopy, hallux valgus corrections or removal of osteosynthesis material. The major reasons for unplanned admissions were inadequate postoperative pain management for overnight admissions and wound infection for admissions after discharge.ResumenObjetivoLos procedimientos de Cirugía Ortopédica y Traumatología (COT) realizados en Unidades de Cirugía Mayor Ambulatoria (CMA) ofrecen importantes ventajas que desaparecen cuando la recuperación postoperatoria no es la...
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
More News: Academia | Anesthesia | Anesthesiology | Antidoxidants | Australia Health | Brain | Brain Cancers | Brazil Health | Cardiology | Cardiovascular | Cardiovascular & Thoracic Surgery | Coconut Oil | Coconuts | Computers | Depression | Diabetes | Diets | Drugs & Pharmacology | Enbrel | Endocrinology | Genetics | Grants | Heart | Hyperactivity | Hypertension | Japan Health | Laparotomy | Lisinopril | Medical Ethics | Men | Menopause | Neurology | Neurosurgery | Nutrition | Parenteral Nutrition | Perfusion | Physiology | Reflex Sympathetic Dystrophy | Reproduction Medicine | Sodium | Sodium Chloride | Spinal Cord Injury | Sports Medicine | Statistics | Study | Sweden Health | Toxicology | Training | Universities & Medical Training | Urology & Nephrology | USA Health