Paediatricians for a Healthy Environment

A group of Argentine paediatricians has been combining work on environmental protection and child health for more than 10 years. It appears a basic principle to apply, but the task is turning out to be increasingly challenging and complex. “We can’t clean up a river, or give a family a new house, but we can teach people to put chlorine in the water,” Dr. Stella Maris Gil, the coordinator of the Environmental Paediatric Unit (UPA) at the Pedro de Elizalde Children’s Hospital in the Constitución neighbourhood of Buenos Aires, told IPS. The UPA provides health care with a strong environmental component, educates the public using the hospital, trains doctors and carries out research, explained Gil and other paediatricians belonging to the unit. “The idea arose in the 2001 crisis,” Gil said, referring to the economic and social collapse at the end of that year, when poverty and unemployment reached unprecedented levels in Argentina and also had an impact on health. “We were seeing a lot of illness connected to poor living conditions: respiratory diseases, gastroenteritis, skin infections … So we decided to give courses on the impact of environmental pollution on health, and we devised a project aimed at protecting the environment in order to provide better health care for children,” she said. The project, which gave rise to the UPA, had a healthcare component “with strong environmental awareness,” Gil said, ...
Source: IPS Inter Press Service - Health - Category: Global & Universal Authors: Tags: Active Citizens Civil Society Development & Aid Environment Featured Headlines Health Human Rights Latin America & the Caribbean Poverty & MDGs Regional Categories Women's Health Argentina Maternal and Child Health Pollution Source Type: news

Related Links:

ConclusionThere is need to improve both the knowledge base and comfort level of pediatricians in counseling their patients during vaccine recommendations. Otolaryngologists have a critical role in providing education to physicians, trainees, and the general public in the effort to combat the epidemic of HPV-associated head and neck cancer.
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Conclusion: Our findings establish PLAC8 as a central mediator of cell growth in a subset of human PanNET, providing evidence for the existence of distinct molecular subtypes within this class of tumors.
Source: Neuroendocrinology - Category: Endocrinology Source Type: research
CONCLUSIONS: We report the delayed diagnosis of CAIS in female Indonesian patients with a history of inguinal hernia in childhood. An early diagnosis of CAIS is essential for appropriate clinical management, as well as assessing familial risk. Increasing awareness among clinicians is paramount, and we encourage a CAIS diagnosis to be considered in any patient presenting with female appearance and inguinal hernia. PMID: 31012339 [PubMed - as supplied by publisher]
Source: Journal of Investigative Surgery - Category: Surgery Tags: J Invest Surg Source Type: research
In conclusion, the spectrum of autoimmune reactions induced by immune-checkpoint inhibitors should be restricted in the near future to only these specific favorable autoimmune mechanisms. In this way, the unnecessary autoimmune reactions/autoaggressions could be avoided (a better quality of life), and treatment specificity and efficiency should increase (a higher response rate for melanoma therapy).
Source: Melanoma Research - Category: Cancer & Oncology Tags: REVIEW ARTICLES Source Type: research
Long noncoding RNA X-inactive specific transcript (XIST) was confirmed to participate in the development of many cancers. However, the function of XIST in malignant melanoma (MM) remained largely unknown. In the current study, we found that the XIST expression level was upregulated in MM tissues and cell lines. In addition, the growth rate of MM cells transfected with silencing XIST was significantly decreased compared with that with silencing normal control. XIST knockdown inhibited proliferation and migration in MM cells and increased the oxaliplatin sensitivity of oxaliplatin-resistant MM cells. Bioinformatics analysis ...
Source: Melanoma Research - Category: Cancer & Oncology Tags: ORIGINAL ARTICLES: Basic science Source Type: research
The recently developed therapeutic strategies have led to unprecedented improvements in the control of metastatic melanoma and in the survival of specific subgroups of patients. However, drug resistance, low response rates, and undesired side effects make these treatments not suitable or tolerable for all the patients, and chemotherapeutic treatments appear still indispensable, at least for subgroups of patients. New combinatory strategies are also under investigation as tailored treatments or salvage therapies, including combined treatments of immunotherapy with conventional chemotherapy. On this basis, and in considerati...
Source: Melanoma Research - Category: Cancer & Oncology Tags: ORIGINAL ARTICLES: Translational research Source Type: research
Patients diagnosed with metastatic melanoma have varied clinical courses, even in patients with similar disease characteristics. We examine the impact of initial stage of melanoma diagnosis, BRAF status of primary melanoma, and receiving adjuvant therapy on postmetastatic overall survival (pmOS). We studied melanoma patients presenting to Perlmutter Cancer Center at New York University and prospectively enrolled in New York University melanoma biospecimen database and followed up on protocol-driven schedule. Patients were stratified by stage at initial melanoma diagnosis as per AJCC 7th ed. guidelines. pmOS was determined ...
Source: Melanoma Research - Category: Cancer & Oncology Tags: ORIGINAL ARTICLES: Clinical research Source Type: research
The gut microbiota impacts response to immunotherapy in cancer patients. We sought to evaluate the role of physiologic colonic fluorine-18-fluorodeoxyglucose (18F-FDG) uptake, a test that was recently shown to reflect colonic bacterial load, as a possible predictor for response to immunotherapy. We carried out a retrospective study in metastatic melanoma patients who received the immune checkpoint inhibitor ipilimumab as first-line therapy. All patients underwent an 18F-FDG PET scan before treatment initiation. The primary outcome was defined as response to treatment according to the RECIST criteria. Regions of interest we...
Source: Melanoma Research - Category: Cancer & Oncology Tags: SHORT COMMUNICATIONS Source Type: research
This study demonstrates that treatment with anti-PD-1 antibodies may impair glucose metabolism, as measured by increasing HbA1c levels.
Source: Melanoma Research - Category: Cancer & Oncology Tags: SHORT COMMUNICATIONS Source Type: research
We describe a unique case of conception and pregnancy, with successful maternal and foetal outcomes, in a patient with metastatic melanoma who had received combination anti-CTLA-4 and anti-PD1 therapy. A 32-year-old G0P0 lady, with a 10-year history of infertility of unclear cause, was found to be 7 weeks pregnant after 14 months of nivolumab maintenance therapy, having previously received combination ipilimumab and nivolumab. Nivolumab was ceased upon discovery of pregnancy in the first trimester. The patient had an uneventful pregnancy, followed by spontaneously premature labour, and delivered by caesarean section at 33 ...
Source: Melanoma Research - Category: Cancer & Oncology Tags: SHORT COMMUNICATIONS Source Type: research
More News: Abdominal Wall Repair | Alcoholism | Argentina Health | Cancer | Cancer & Oncology | Chemistry | Child Abuse | Child Development | Children | Dengue Fever | Education | Environmental Health | Gastroenteritis | Gastroenterology | Gastroschisis | Gastroschisis Repair | Government | Hantavirus | Health | Health Management | Hemorrhoids | Hospitals | International Medicine & Public Health | Leukemia | Parasitic Diseases | Parasitology | Pediatrics | Pregnancy | Premature Birth | Respiratory Medicine | Skin | Smokers | Substance Abuse | Teaching | Thyroid | Thyroid Cancer | Toxicology | Training | Unemployment | Universities & Medical Training | WHO | Women | Workshops | X-Ray