Paediatricians for a Healthy Environment
A group of Argentine paediatricians has been combining work on environmental protection and child health for more than 10 years. It appears a basic principle to apply, but the task is turning out to be increasingly challenging and complex. “We can’t clean up a river, or give a family a new house, but we can teach people to put chlorine in the water,” Dr. Stella Maris Gil, the coordinator of the Environmental Paediatric Unit (UPA) at the Pedro de Elizalde Children’s Hospital in the Constitución neighbourhood of Buenos Aires, told IPS. The UPA provides health care with a strong environmental component, educates the public using the hospital, trains doctors and carries out research, explained Gil and other paediatricians belonging to the unit. “The idea arose in the 2001 crisis,” Gil said, referring to the economic and social collapse at the end of that year, when poverty and unemployment reached unprecedented levels in Argentina and also had an impact on health. “We were seeing a lot of illness connected to poor living conditions: respiratory diseases, gastroenteritis, skin infections … So we decided to give courses on the impact of environmental pollution on health, and we devised a project aimed at protecting the environment in order to provide better health care for children,” she said. The project, which gave rise to the UPA, had a healthcare component “with strong environmental awareness,” Gil said, ...
David Porras, Esther Nistal, Susana Mart ínez-Flórez, Javier González-Gallego, María Victoria García-Mediavilla, Sonia Sánchez-Campos
Antonio Macci ò, Silvia Busquets, Clelia Madeddu, Josep M. Argilés
Nikitas N. Nomikos, Pantelis T. Nikolaidis, Caio V. Sousa, Apostolos E. Papalois, Thomas Rosemann, Beat Knechtle
Publication date: Available online 17 December 2018Source: Redox BiologyAuthor(s): Jayshree Hirpara, Jie Qing Eu, Joanna Kia Min Tan, Andrea L. Wong, Marie-Veronique Clement, Kong Li Ren, Naoto Ohi, Takeshi Tsunoda, Jianhua Qu, Boon Cher Goh, Shazib PervaizAbstractThe ability to selectively eradicate oncogene-addicted tumors while reducing systemic toxicity has endeared targeted therapies as a treatment strategy. Nevertheless, development of acquired resistance limits the benefits and durability of such a regime. Here we report evidence of enhanced reliance on mitochondrial oxidative phosphorylation (OXPHOS) in oncogene-ad...
Dalton Trans., 2019, Advance Article DOI: 10.1039/C8DT03266A, PaperLeila Tabrizi, Lukman O. Olasunkanmi, Olatomide A. Fadare The cyclometalated ruthenium(II) complex was synthesized and studied for cytotoxicity. The interaction of Ru(II) complex with COX-2 was studied by experimental and molecular docking. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Chem. Commun., 2019,55,63-66 DOI: 10.1039/C8CC08866G, CommunicationYan Li, Longjie Li, Xunbo Lu, Yulong Bai, Yufan Wang, Yuzhou Wu, Fangrui Zhong Inspired by the heme iron-catalyzed radical insertion of dioxygen to the tryptophan indole ring, herein we utilize alkylperoxy radical species as a coupling partner to trigger a peroxycyclization of readily accessible tryptophan derivatives and enable the first synthesis of peroxypyrroloindolenines. The content of this RSS Feed (c) The Royal Society of Chemistry
Analyst, 2019, Advance Article DOI: 10.1039/C8AN02092B, PaperAritri Ghosh, Sreyan Raha, Susmita Dey, Kabita Chatterjee, Amit Roy Chowdhury, Ananya Barui FTIR spectroscopy and Raman spectroscopy of biological analytes are increasingly explored as screening tools for early detection of cancer. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
India's federal drug regulator said on Tuesday a Reuters report that Johnson&Johnson knew for decades that cancer-causing asbestos lurked in its baby powder was "under consideration".
Abstract Free radicals are closely related to the occurrence and development of aging, cancer and inflammation. In this paper, the microbial transglutaminase (MTGase) was used as a catalyst to graft the collagen peptide (COP) molecules on the amino group of carboxymethyl chitosan sulfate (CMCS) to improve the antioxidant effects. FT-IR and NMR spectroscopy were used to confirm the successful grafting of COP to CMCS. Degree of substitution (DS) of CMCS-COP could be controlled by adjusting the reaction conditions. With the increase of concentration, the ability of each sample on scavenging capacity and reducibility ...
Publication date: Available online 17 December 2018Source: Meta GeneAuthor(s): Andrea Mary Francis, R. Ramya, Nalini Ganesan, P. Kumarasamy, Solomon F.D. Paul, A.K. Munirajan, M. DivyaAbstractThe most common cancer in women is breast cancer, and it poses serious health issues in women, leading to increased mortality rates. Estrogen and its metabolites have been established as risk factors for breast cancer. Determining the role of genetic variants having functional involvement in regulating the estrogen concentration and detoxifying the toxic estrogen metabolites through estrogen hydroxylation by CYP1A1, CYP1B1, and catech...
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