Successful completion of an imported fire ant cluster immunotherapy protocol.

Successful completion of an imported fire ant cluster immunotherapy protocol. Ann Allergy Asthma Immunol. 2019 Apr 24;: Authors: Beveridge GB, Tankersley MS PMID: 31028893 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: Ann Allergy Asthma Immunol Source Type: research

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ConclusionsThe trial demonstrated a favorable safety profile of the SQ HDM SLIT tablet in Japanese adult patients with AA. The treatment appeared to be efficacious in patients requiring rescue medication (ie, short-acting β2-agonist) at baseline in the efficacy assessment using asthma exacerbation during inhaled corticosteroid reduction (JapicCTI number 121847).
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
This article reviews the available literature, including a large number of randomized controlled trials, meta-analyses, and real-life studies as well, on the outcomes of SCIT and SLIT concerning the treatment critical issues of the two routes, that are efficacy, safety, cost-effectiveness, and compliance to treatment. Expert opinion: SCIT and SLIT are similarly effective in treating patients with respiratory allergy, providing, based on the induction of typical changes in the immunologic response, an early control of symptoms that steadily increases during the treatment and, once reached the recommended duration of three y...
Source: Expert Review of Respiratory Medicine - Category: Respiratory Medicine Tags: Expert Rev Respir Med Source Type: research
This study evaluated the clinical efficacy of subcutaneous allergen immunotherapy in adult patients with allergic rhinitis based on the serum level of vitamin D. Patients with persistent allergic rhinitis and positivity for skin prick test were evaluated by Sino-nasal Outcome Test (SNOT-22) and Mini Rhinoconjunctivitis Quality of Life Questionnaire (MiniRQLQ) before subcutaneous allergen immunotherapy and during the maintenance phase to assess the relation of the serum level of vitamin D and the clinical efficacy of immunotherapy. After immunotherapy, the greatest reduction in SNOT-22 scores were reported in patients with ...
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
CONCLUSIONS: UR-SCIT with tyrosine-adsorbed HDM extract conducted in an outpatient clinic was tolerable in patients with AD and AR. UR-SCIT can be a useful method to start a SCIT in patients with AD and AR. PMID: 31552719 [PubMed]
Source: Allergy, Asthma and Immunology Research - Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research
Conditions:   Allergic Asthma Due to Dermatophagoides Pteronyssinus;   Allergic Asthma Due to Dermatophagoides Farinae;   Allergic Rhinitis Due to House Dust Mite Interventions:   Drug: ODACTRA 12 SQ-HDM Sublingual Tablet;   Drug: Placebo oral tablet Sponsors:   Bispebjerg Hospital;   University of Copenhagen;   Allergy- and pulmonary Clinic, Vanloese.;   ALK-Abelló A/S;   Lund University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
To assess the safety and efficacy of an oral immunotherapy regimen in patients with allergy to lipid transfer proteins (LTPs).
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Short report Source Type: research
ConclusionThe trial demonstrated a favorable safety profile of the SQ HDM SLIT-tablet in Japanese adult patients with AA. The treatment appeared to be efficacious in patients requiring rescue medication (i.e., SABA) at baseline in the efficacy assessment using asthma exacerbation during ICS reduction (JapicCTI number 121847).
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 12 September 2019Source: The LancetAuthor(s): R Sharon Chinthrajah, Natasha Purington, Sandra Andorf, Andrew Long, Katherine L O'Laughlin, Shu Chen Lyu, Monali Manohar, Scott D Boyd, Robert Tibshirani, Holden Maecker, Marshall Plaut, Kaori Mukai, Mindy Tsai, Manisha Desai, Stephen J Galli, Kari C NadeauSummaryBackgroundDietary avoidance is recommended for peanut allergies. We evaluated the sustained effects of peanut allergy oral immunotherapy (OIT) in a randomised long-term study in adults and children.MethodsIn this randomised, double-blind, placebo-controlled, phase 2 study, we enrolle...
Source: The Lancet - Category: General Medicine Source Type: research
THURSDAY, Sept. 12, 2019 -- Allergy immunotherapy (AIT) is associated with a decreased risk for asthma progression, particularly in younger patients, according to a study published online Aug. 13 in Allergy. Jochen Schmitt, M.P.H., from the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
ConclusionAs new data arise, revisions might soon be needed allowing AIT in the cases of patients treated with ACE inhibitors and beta-blockers, in elderly patients and in patients with concomitant autoimmune diseases and neoplasias in remission. The decision to prescribe AIT is always tailor-made, balancing risk vs benefit. Creating globally accepted guidelines would help Allergologists in their decision making.
Source: Clinical and Translational Allergy - Category: Allergy & Immunology Source Type: research
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