Loss of Msh2 and a single-radiation hit induce common, genome-wide, and persistent epigenetic changes in the intestine

Mismatch repair (MMR)-deficiency increases the risk of colorectal tumorigenesis. To determine whether the tumors develop on a normal or disturbed epigenetic background and how radiation affects this, we quanti...

Source: Clinical Epigenetics - April 27, 2019 Category: Research Authors: Maria Herberg, Susann Siebert, Marianne Quaas, Torsten Thalheim, Karen Rother, Michelle Hussong, Janine Altm üller, Christiane Kerner, Joerg Galle, Michal R. Schweiger and Gabriela Aust Tags: Research Source Type: research