Diagnostic challenges in congenital cytomegalovirus infection in pregnancy: A case report

Conclusion: A meticulous anatomy survey in mid-trimester remains the norm and ultrasound soft markers should prompt comprehensive testing for viral infections in pregnancy.
Source: Case Reports in Womens Health - Category: OBGYN Source Type: research

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Membranous nephropathy and anti –glomerular basement membrane glomerulonephritis are characterized by the deposition of antibodies that recognize specific glomerular epitopes. These antibodies may develop in autoimmune diseases, after exposure to new antigens or after passive maternal transfer, such as in neonatal membranous nep hropathy secondary to in utero transfer of anti–neutral endopeptidase protein Igs. In this issue of Kidney International, Abrahamson et al. reported a murine model of passive anti–glomerular basement membrane disease caused by antibody transfer from pregnant mice to their offspring.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Commentary Source Type: research
ConclusionsOur study showed that machine learning-based multiparametric MR imaging radiomics could accurately distinguish aggressive from non-aggressive PTC preoperatively. This approach may be helpful for informing treatment strategies and prognosis of patients with aggressive PTC.
Source: European Journal of Radiology - Category: Radiology Source Type: research
Conclusion cCMV is a preventable cause of serious congenital disability and death. Prevention opportunities are being missed because most women are not aware of cCMV or how to reduce their risk of infection in pregnancy, in part due to poor health professional awareness. New strategies to disseminate cCMV information to the community and to support health professionals to embed cCMV advice within routine pregnancy counselling is required. PMID: 30306881 [PubMed - as supplied by publisher]
Source: Infectious Disorders Drug Targets - Category: Infectious Diseases Authors: Tags: Infect Disord Drug Targets Source Type: research
Doctors say the transfer of an infection from a pregnant mother to a newborn can pose a serious threat to the baby, including deafness and a malformed brain. Three congenital infections — syphilis, cytomegalovirus (CMV), and HIV — are especially problematic in Texas, reports the July issue of Texas Medicine magazine.
Source: TMA News Room - Category: Consumer Health News Source Type: news
Abstract From the discovery of the Zika virus (ZIKV) in 1947 in Uganda (Africa), until its arrival in South America, it was not known that it would affect human reproductive life so severely. Today, damagetothe central nervous system is known to be multiple, and microcephaly is considered the tip of the iceberg. Microcephaly actually represents the epilogue of this infection ’ s devastating process on the central nervous system of embryos and fetuses. As a result of central nervous system aggression by the ZIKV, this infection brings the possibility of arthrogryposis, dysphagia, deafness and visual impairment. All of...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
To protect your baby from a disabling disease, first you have to know that it exists.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Cytomegalovirus Pregnancy and Childbirth Ears and Hearing Deafness Disabilities Cochlear Implants Families and Family Life Source Type: news
Congenital cytomegalovirus (CMV) infection represents a relevant cause of deafness and neurological damage in newborns. Intrauterine CMV transmission might result after primary or nonprimary infections, though at different rates (30% versus 0.2%, respectively). At present, a prenatal diagnosis of CMV infection is based mainly on maternal serology, the detection of CMV-DNA in amniotic fluid and fetal blood, and ultrasound (US) and magnetic resonance imaging (MRI). Recent evidences suggest that congenital CMV infection may be an immune-mediated disease and that evaluation of humoral and especially T-cell immunities may impro...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Minireviews Source Type: research
Queensland mother Rebekka Murray contracted Cytomegalovirus (CMV) for the first time while pregnant, passing the virus on to her unborn baby.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
A study in Brazil of 70 babies whose mothers had confirmed Zika infections found that nearly 6 percent had hearing loss, adding a new complication to the list of ills the virus can cause when women are infected during pregnancy. The Brazilian study, published on Tuesday in the U.S. Centers for Disease Control and Prevention’s weekly report on death and disease, confirmed less rigorous reports of deafness among infants born to mothers with Zika infections. The finding is part of an effort to fully characterize the harm caused by the Zika virus during pregnancy. The virus is best known for causing the severe birth defe...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
In this study, two interferon gamma release assays (IGRA), the CMV enzyme-linked immunosorbent spot (ELISPOT) and CMV QuantiFERON assays, detecting CMV-specific CMI were compared. These assays were performed for 80 CMV-infected (57 primarily and 23 nonprimarily) pregnant women and 115 controls, including 89 healthy CMV-seropositive pregnant women without active CMV infection, 15 CMV-seronegative pregnant women, and 11 seropositive or seronegative nonpregnant women. Statistical tests, including frequency distribution analysis, nonparametric Kruskal-Wallis equality-of-populations rank test, Wilcoxon rank sum test for equalit...
Source: Journal of Clinical Microbiology - Category: Microbiology Authors: Tags: Immunoassays Source Type: research
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