Stem cells reduce pain of knee arthritis: Mayo Clinic Radio Health Minute

Many people suffer from painful and debilitating osteoarthritis of the knee. In a recent study, experts at Mayo Clinic tested?the benefit of using bone marrow stem cells to reduce arthritic pain and disability.? In this Mayo Clinic Radio Health Minute, Dr. Shane Shapiro?talks about how stem cell therapy offers great hope for the future of [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news

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Authors: ┼×ahin ┼×, Tuncel SA, Salimi K, Bilgiç E, Korkusuz P, Korkusuz F Abstract Osteoarthritis (OA) is a common form of arthritis, which is characterized by progressive degradation of joint cartilage resulting in pain, joint stiffness, deformity and disability that is also recently related to an increased incidence of mortality. Inhibition of the extracellular matrix (ECM) production by chondrocytes and accumulation of catabolic mediators associated with matrix degradation are the cause of OA. Nonsurgical treatments for OA can be characterised as symptom-modifying or disease-modifying approaches. It's est...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research
This study didn't measure whether receiving the cardiosphere-derived cells extended lifespans, so we have a lot more work to do. We have much to study, including whether CDCs need to come from a young donor to have the same rejuvenating effects and whether the extracellular vesicles are able to reproduce all the rejuvenating effects we detect with CDCs." Cardiac and systemic rejuvenation after cardiosphere-derived cell therapy in senescent rats Cardiosphere-derived cell (CDC) therapy has exhibited several favourable effects on heart structure and function in humans and in preclinical models; however,...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In conclusion, documentation is important, a critical part of advocacy and the development process at the larger scale. It isn't just words, but rather a vital structural flow of information from one part of the larger community to another, necessary to sustain progress in any complex field. We would all do well to remember this - and to see that building this documentation is an activity in which we can all pitch in to help. Evidence Suggests that, at Least in Earlier Stages, Alzheimer's Disease Blocks Rather than Destroys Memories https://www.fightaging.org/archives/2017/07/evidence-suggests-that-at-least-in-ea...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Fight Aging! provides a weekly digest of news and commentary for thousands of subscribers interested in the latest longevity science: progress towards the medical control of aging in order to prevent age-related frailty, suffering, and disease, as well as improvements in the present understanding of what works and what doesn't work when it comes to extending healthy life. Expect to see summaries of recent advances in medical research, news from the scientific community, advocacy and fundraising initiatives to help speed work on the repair and reversal of aging, links to online resources, and much more. This content is...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
In this study we demonstrate the use of clustered regularly interspaced short palindromic repeats (CRISPR)-based epigenome editing to alter cell response to inflammatory environments by repressing inflammatory cytokine cell receptors, specifically TNFR1 and IL1R1. This has applications for many inflammatory-driven diseases. It could be applied for arthritis or to therapeutic cells that are being delivered to inflammatory environments that need to be protected from inflammation." In chronic back pain, for example, slipped or herniated discs are a result of damaged tissue when inflammation causes cells to create ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Many people suffer from painful and debilitating osteoarthritis of the knee. In a recent study, experts at Mayo Clinic tested?the benefit of using bone marrow stem cells to reduce arthritic pain and disability.? In this Mayo Clinic Radio Health Minute, Dr. Shane Shapiro?talks about how stem cell therapy offers great hope for the future of [...]
Source: News from Mayo Clinic - Category: Databases & Libraries Source Type: news
Introduction: Arthritis is a major cause of disability and chronic pain, affecting at least 3.85 million people within Australia at a cost of>$23.9 billion each year. World wide it is considered the fourth leading cause of disability.
Source: Journal of Science and Medicine in Sport - Category: Sports Medicine Authors: Tags: 69 Source Type: research
Cutting-edge stem cell advances have been used to create a new "living hip replacement" that could potentially revolutionise the treatment of arthritis and other joint conditions.The collaboration between Washington University School of Medicine and Cytex Therapeutics has found a way to grow new cartilage tissue using stem cells, while giving the material the ability to release anti-inflammatory molecules to fight off arthritis. This could mark a significant advance compared to current hip replacement approaches.How the living hip replacement works Published in the Proceedings of the National Academy of Sciences,...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
This study also provides encouraging preliminary evidence of efficacy. Larger and controlled long-term studies are now mandatory to confirm whether this new strategy of cell therapy can improve pain and induce structural benefit in osteoarthritis.
Source: Stem Cells Translational Medicine - Category: Stem Cells Authors: Tags: Adipose-Derived Stem Cells, Human Clinical Articles Source Type: research
Your achievements A massive thank you to everyone who ran, hosted coffee mornings and bake sales, jumped out of planes and trekked across the country and indeed the world to fundraise for us. More than 1,300 of you took on a challenge or donated your time and fundraising skills in 2015. Together, you raised over £780,000! If you’d like to join Team A in 2016 and help raise money for our work, have a look at our events or contact localfundraising@arthritisresearchuk.org Improving care for people with arthritis In 2015 we continued to support healthcare professionals to provide the best care to people with art...
Source: Arthritis Research UK - Category: Rheumatology Source Type: news
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