Use Profile of Magnesium Sulfate in Anesthesia in Brazil

Conclusions: Magnesium sulfate is an important adjuvant drug in the practice of anesthesia, with several clinical effects and a low incidence of adverse events when used at recommended doses. Introduction Magnesium is the fourth most common ion in the body, and it participates in several cellular processes, including protein synthesis, neuromuscular function and stability of nucleic acid, as well as regulating other electrolytes such as calcium and sodium. Magnesium acts as a cofactor in protein synthesis, neuromuscular function and stability and the function of nucleic acids. It is a component of adenosine 5-triphosphatases and an endogenous regulator of other electrolytes. It is a calcium antagonist because it is a non-competitive inhibitor of calcium channels with inositol triphosphate. Magnesium modulates sodium and potassium currents and, as a consequence, interferes with the transmembrane potential. It is a central nervous system depressant, antagonizing N-methyl-D-aspartate (NMDA) and inhibiting the release of catecholamines (Herroeder et al., 2011). Some studies have shown that the use of magnesium sulfate as an adjunct in anesthesia reduces intraoperative consumption of anesthetics (Koinig et al., 1998; Seyhan et al., 2006; Ryu et al., 2008; Forget and Cata, 2017). It also provides better analgesia and reduces the amount of morphine used in the postoperative period (Mentes et al., 2008; Dabbagh et al., 2009; Hwang et al., 2010). Studies in clinical practice ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research

Related Links:

In this study, 5% w/v SMP dispersion was acidified to pH 2.4–3.0 using citric acid and heated at different conditions. Lowering pH resulted in dissolution of colloidal calcium phosphate from casein micelles, corresponding to lowered turbidity and reduced hydrodynamic diameter of dispersions. When heated for 10 min at different temperatures, 70 °C was the most effective to produce transparent dispersions; whereas a shorter heating time between 2 and 60 min was desired at 90 °C. The decreased turbidity after heating was attributed to weakened hydrophobic interaction between casein molecules based on f...
Source: Food Hydrocolloids - Category: Food Science Source Type: research
Publication date: Available online 14 October 2019Source: Food ChemistryAuthor(s): Jianghao Sun, Craig S. Charron, Janet A. Novotny, Bing Peng, Liangli Yu, Pei ChenAbstractBroccoli is a popular brassica vegetable and its consumption may decrease the occurrence of cancer in certain populations. To gain insight into the metabolites that may induce physiological responses to broccoli intake, a non-targeted metabolomic approach and a targeted approach for analysis of glucosinolate metabolites were developed using high resolution accurate mass spectrometry. A human study was conducted in which 6 subjects consumed a single meal ...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 14 October 2019Source: Food ChemistryAuthor(s): Andreas Eisenreich, Benjamin Sachse, Rainer Gürtler, Birgit Dusemund, Oliver Lindtner, Bernd SchäferAbstractOpium alkaloids such as morphine and thebaine occur in the latex of Papaver somniferum varieties. Some varieties are used for both, pharmaceutical opium alkaloid generation and poppy seed production for food use. Poppy seeds can be contaminated with opium alkaloid-containing latex, e.g. during harvesting. In recent years, poppy seed contamination with opium alkaloids, including thebaine, gave repeatedly reasons for concern in...
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 13 October 2019Source: Journal of Molecular LiquidsAuthor(s): Hany M.Abd El-Lateef, Zeinab A. Abdallah, Mohamed S.Mohamed AhmedAbstractEthyl 2-(1,2,3,6-tetrahydro-6-oxo-2-thioxopyrimidin-4-yl)ethanoate (EOTPE) was synthesized by a facile and cost-effective method. The structure confirmation of the synthesized EOTPE was performed by different spectroscopic methods. The corrosion inhibition action of EOTPE in pickling acids (1.0 N HCl and1.0 N H2SO4) at different temperatures (30–60 °C) was tested by various surface and corrosion methods, including open circuit potential (...
Source: Journal of Molecular Liquids - Category: Molecular Biology Source Type: research
Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Elumalai Preetham, Abdul Salam Rubeena, Baskaralingam Vaseeharan, Mukesh Kumar Chaurasia, Jesu Arockiaraj, Rolf Erik OlsenAbstractThe study is carried out to understand the antimicrobial and immunological response of a potential immune molecule lectin, MmLec isolated from haemolymph of Speckled shrimp, Metapenaeus monoceros. MmLec was purified using mannose coupled Sepharose CL-4B affinity chromatography, which was further subjected on SDS-PAGE to ascertain the distribution of their molecular weight. Sugar binding specificity assay w...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Publication date: Available online 13 October 2019Source: Advances in Biological RegulationAuthor(s): Veronica Balatti, Carlo M. CroceAbstractWe established that loss of miR-15a/16–1 genes on chromosome 13q14 is the most common alteration in Chronic Lymphocytic Leukemia (CLL) and that miR-15/16 are crucial negative regulator of BCL-2, an antiapoptotic gene overexpressed in most CLLs and in many other malignancies. We have also shown that miR-15/16 target ROR1, a cell surface receptor for Wnt5a which can enhance growth/survival of CLL cells. Interestingly, ROR1 is expressed by many cancers, but not by normal adult tis...
Source: Advances in Biological Regulation - Category: Biology Source Type: research
House Appropriations Committee Chairwoman Nita Lowey (D-NY) has announced that she will retire at the end of the current Congress. The Chairwoman of the Appropriations Subcommittee on Energy and Water Development, Marcy Kaptur (D-OH), is next in line to lead the full panel and said, "I am interested in placing my name for consideration as the committee member with the most experience and seniority when the time is appropriate." Representative Rosa DeLauro (D-CT) has also expressed an interest in running for the sought-after House Appropriations Committee chair in 2021. However, if Democrats lose control of the Ho...
Source: Public Policy Reports - Category: Biology Authors: Source Type: news
Publication date: 1 December 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 184Author(s): Maosheng Xu, Kunsong Zhang, Yubing Liu, Jie Wang, Ke Wang, Yuanqing ZhangAbstractThe treatment of cancer has always been a worldwide problem. The combination of chemotherapy and other therapies would be a promising therapy strategy. Photothermal therapy (PTT) does not cause serious side effects and has dual control of time and space, which was considered to be a good method for combination with chemotherapy. Here, we modified multifunctional nanosheets based on in-situ gold nanoparticles (Au NPs) grown molybdenum disulfide...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Publication date: Available online 13 October 2019Source: Sensors and Actuators B: ChemicalAuthor(s): Zakie Anajafi, Mahmoud Naseri, G. NeriAbstractIn this paper, the synthesis, characterization and sensing properties of SmFeO3/ZnO nanocomposite synthesized by the thermal treatment method, is reported. The morphological and microstructural characteristics of the synthesized composite nanopowders and single SmFeO3 and ZnO components, were analyzed by Scanning Electron Microscopy-Electron Dispersive X-ray (SEM-EDX), X-ray diffraction (XRD), Fourier Transform-Infrared (FT-IR) spectroscopy and Photoluminscence (PL). Characteri...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
Publication date: Available online 13 October 2019Source: Sensors and Actuators B: ChemicalAuthor(s): Chenyu Yao, Limin Xiao, Shoufei Gao, Yingying Wang, Pu Wang, Ruifeng Kan, Wei Jin, Wei RenAbstractWe demonstrated the sensitive CO detection in a novel hollow-core negative curvature fiber (HC-NCF) with infrared laser absorption at 2.3 µm. The HC-NCF consists of a single ring of eight nontouching silica capillaries around the air core, providing a single-mode light delivery of the 2.3-µm distributed feedback laser. A high coupling efficiency of 90% was achieved with the aid of optimal free-space coupling...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
More News: Academia | Anesthesia | Anesthesiology | Arrhythmia | Asthma | Atrial Fibrillation | Back Pain | Belgium Health | Bleeding | Brain | Brain Cancers | Brazil Health | Bronchoscopy | Calcium | Cancer | Cancer & Oncology | Cancer of the Uterus | Carcinoma | Cardiac Arrhythmia | Cardiology | Cardiovascular | Cardiovascular & Thoracic Surgery | Children | Cholecystectomy | Chronic Pain | Clinical Trials | Clonidine | Coronary Artery Bypass Graft | Depression | Dialysis | Diprivan | Drugs & Pharmacology | Education | Emergency Medicine | Endotracheal Intubation | Esophagus Cancer | Furosemide | Gastric (Stomach) Cancer | Gastroenterology | Heart | Heart Attack | Hemodialysis | Hemorrhagic Stroke | Hormones | Hysterectomy | Induction of Labor | Insulin | Intensive Care | Jordan Health | Laparoscopy | Laryngoscopy | Lidoderm | Lower Endoscopy | Magnesium | Medical Ethics | Men | Middle East Health | Morphine | Neurology | Neuroscience | Neurosurgery | OBGYN | Opthalmology | Oral Cancer | Orthopaedics | Pain | Pain Management | Pediatrics | Perinatology & Neonatology | PET Scan | Pheochromocytoma | Physiology | Postnatal Depression | Potassium | Pre-eclampsia | Pregnancy | Propofol | Prostatectomy | Reflex Sympathetic Dystrophy | Reproduction Medicine | Respiratory Medicine | Saudi Arabia Health | Sevoflurane | Sodium | Statistics | Study | Subarachnoid Hemorrhage | Tetanus | Tonsillectomy and Adenoidectomy | Tonsillitis | Toxicology | Tracheal Cancer | Tramadol | UK Health | Ultane | Universities & Medical Training | USA Health | Women