EU Panel Backs Dolutegravir/Lamivudine Combo Pill for HIV EU Panel Backs Dolutegravir/Lamivudine Combo Pill for HIV

Dovato contains 50 mg dolutegravir and 300 mg lamivudine and would be the first once-daily, single-pill, completed 2-drug regimen for treatment of HIV in Europe.International Approvals
Source: Medscape Pharmacist Headlines - Category: Drugs & Pharmacology Tags: HIV/AIDS News Alert Source Type: news

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CONCLUSIONS: Extensive change in sexual behaviour occurred across eastern and southern Africa during the period of scale-up of antiretroviral therapy programmes. This includes increasing multiple and non-regular partnerships, but their potential effects on population-level sexual risks were often offset by parallel increases in condom use. Strengthening condom programmes and reintegrating communication about behavioural dimensions into combination prevention programmes could help countries to meet international targets for reductions in HIV incidence. PMID: 31225953 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Authors: El Chaar E, Urtula AB, Georgantza A, Cruz S, Fallah-Abed P, Castaño A, Abitbol T, Warner MM Abstract This multicenter study retrospectively evaluated implant survival and bone growth in atrophic ridges that were augmented with titanium mesh and 100% mineralized solvent-dehydrated bone allografts (MSDBA). A secondary objective of this study was to evaluate differences in outcomes by diagnostic model type. Titanium mesh was shaped on a diagnostic wax-up of the patient's jaw: Twenty-three patients (Group 1) had wax-ups on dental stone models, and 16 patients (Group 2) had wax-ups on models fabricated w...
Source: International Journal of Periodontics and Restorative Dentistry - Category: Dentistry Tags: Int J Periodontics Restorative Dent Source Type: research
This article summarizes current knowledge in this field and its application to the process of smoking cessation. Shared decision making in smoking cessation is illustrated by a decision aid created to facilitate the choice between different smoking cessation medications. PMID: 31221484 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
ConclusionsThe use of intraoperative electromagnetic transthoracic nodule localization prior to thoracoscopic resection of small and/or difficult to palpate lung nodules is safe and effective, potentially eliminating the need for direct nodule palpation. Use of this technique aids in minimally invasive localization and resection of small, deep and/or ground-glass lung nodules.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
This Tuesday, the San Francisco Board of Supervisors is scheduled to vote on a proposed ordinance that would ban the sale of cigarettes and marijuana products in the city until the FDA conducts a safety review of these products.The impetus for the proposed ordinance was new data showing that a large proportion of San Francisco youths are still smoking and that the use of marijuana may even be increasing, especially with the recent legalization of recreational marijuana use. The city attorney explained that: " The epidemic is real. It needed attention. We felt it was necessary to step in and make sure we were protectin...
Source: The Rest of the Story: Tobacco News Analysis and Commentary - Category: Addiction Source Type: blogs
Authors: Tang Q, Lu H Abstract Human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) ranks eighth in the global burden of disease, making seriously threatens to global health. Given there is not yet a cure for HIV infection, antiretroviral therapy (ART) holds a key role not only in improving the prognosis of the patients, but also reducing the risk of HIV transmission. The immediate initiation of ART has been recommended in domestic and foreign policies and guidelines, yet the implementation of this strategy is not satisfactory. In developing countries and even in some developed countries, i...
Source: Drug Discoveries and Therapeutics - Category: Drugs & Pharmacology Tags: Drug Discov Ther Source Type: research
We report a case of noninfectious vacuolar interface dermatitis associated with colonic and perianal ulceration in a patient with acquired immunodeficiency syndrome (AIDS), which responded to immunosuppressive treatment. Our findings suggest that interface dermatitis in the setting of AIDS may warrant further gastrointestinal evaluation and may respond to immunosuppression. AbstractWe report a case of noninfectious vacuolar interface dermatitis associated with colonic and perianal ulceration in a patient with acquired immunodeficiency syndrome (AIDS), which responded to immunosuppressive treatment. Our findings suggest tha...
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE REPORT Source Type: research
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Source: Protein Science - Category: Biochemistry Authors: Tags: Full ‐Length Papers Source Type: research
AbstractPurpose of ReviewDifferentiated service delivery (DSD) models were initially developed as a means to combat suboptimal long-term retention in HIV care, and to better titrate limited health systems resources to patient needs, primarily in low-income countries. The models themselves are designed to streamline care along the HIV care cascade and range from individual to group-based care and facility to community-based health delivery systems. However, much remains to be understood about how well and for whom DSD models work and whether these models can be scaled, are sustainable, and can reach vulnerable and high-risk...
Source: Current HIV/AIDS Reports - Category: Infectious Diseases Source Type: research
Sir Elton John, a newly awarded Legion of honor pinned to his suit, joined a call Friday by French President Emmanuel Macron to fund AIDS research and treatment
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
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