Microbiome on the Bone-Anchored Hearing System: A Prospective Study

Conclusion This study provides evidence for a microbiota associated with a bone-anchored hearing implant system. Particularly, S. aureus and S. epidermidis should be considered as relevant bacteria after implantation of the system. Furthermore, the results indicate the possibility of an early identification of patients with an increased susceptibility to adverse skin reaction. Better understanding of the skin microbiota will help to elucidate (i) the microbial interdependencies necessary to maintain healthy skin conditions around BAHS, (ii) how specific bacterial species are involved in BAHS-associated infection and inflammation and (iii) facilitate the development of new antimicrobial strategies. Ethics Statement This study was performed in accordance with the Dutch legislation of Medical Research Involving Human Patients Act and with the ethical standards on human experimentation in the Netherlands. The study was conducted in accordance with the Declaration of Helsinki and was approved by the medical ethical committee of Maastricht University Medical Centre + (MUMC+) (NL50072.068.14) and registered at clinicaltrials.gov (NCT02438618). Consent procedure was in accordance with the study protocol and ISO 14155. Author Contributions TC involved in the execution and analysis of the study. MJ and JvT involved in the design and execution of the study. ML-D involved in the execution of the study. AJ involved in the design and analysis of the study. PS involved in the design o...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research