Complimentary Methods for Multivariate Genome-Wide Association Study Identify New Susceptibility Genes for Blood Cell Traits

This study was approved by the Science and Ethics Committee of the UVRI, the Ugandan National Council for Science and Technology, and the East of England-Cambridge South NHS Research Ethics Committee United Kingdom. Author Contributions SF, DG, MS, and PK designed the study. SF performed the analyses. TC carried out the quality control and imputation. DG, MS, and PK directed the project. SF and ON wrote the manuscript. All authors contributed to the interpretation of the results and writing the article. Funding This work was funded by the Medical Research Council/Uganda Virus Research Institute Uganda Research Unit on AIDS core funding and Wellcome Sanger Institute (Grant No. WT098051), the National Institute for Health Research Cambridge Biomedical Research Centre, and the UK Medical Research Council (Grant MR/K013491/1). SF was funded by National Institutes of Health (NIH) grant U01MH115485 and The Uganda Medical Informatics Centre (UMIC). DG was funded by MR/S003711/1. Computational support from UMIC was made possible through funding from the Medical Research Council (MC_EX_MR/L016273/1). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments SF wishes to acknowledge his exchange fellowship from the African Partnership for Chronic Disease Research (APCDR), MUII-plus bioinformatics grant; support of the ...
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research