TRPV1 Channel Contributes to the Behavioral Hypersensitivity in a Rat Model of Complex Regional Pain Syndrome Type 1

This study was carried out in accordance with National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. 8023, revised 1978) and approved by the Animal Ethics Committee of Zhejiang Chinese Medical University. Author Contributions QH performed the western blot, immunostaining, and behavioral test. QW performed the patch clamp experiments. CW supervised the patch clamp experiments. QH and BoyuL performed the behavioral test. YT, XS, and JF analyzed the data and reviewed the manuscript. BoyiL designed, supervised the study, and wrote the manuscript. Funding This project was supported by funding from the Zhejiang Provincial Natural Science Funds for Distinguished Young Scholars (LR17H270001), the National Natural Science Foundation of China (81873365 and 81603676), Qianjiang Talent Program (QJD1702020) to BoyiL, the National Natural Science Foundation of China (81770407), the High-level Talent Support Project Hebei Province (No. A2017005070) to CW, and the National Natural Science Foundation of China (81574056) to XS. Contents are solely the responsibility of the authors and do not necessarily represent the views of the funders. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. References Abdulla, F. A., and Smith, P. A. (2001). Axotomy- and autotomy-induced changes in Ca2+ and...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research