A natural diarylheptanoid protects cortical neurons against oxygen –glucose deprivation‐induced autophagy and apoptosis

ConclusionsThese results demonstrate that AO ‐2 increases resistance of cortical neurons to OGD/R by decreasing autophagy and cell apoptosis, which involves an mTOR‐dependent mechanism.

Source: Journal of Pharmacy and Pharmacology - April 24, 2019 Category: Drugs & Pharmacology Authors: Qiaoyun Shi, Qinghua Zhang, Yinghui Peng, Xiaoqi Zhang, Ying Wang, Lei Shi Tags: Research Paper Source Type: research