Molecular basis for the association between depression and circadian rhythm - Varinthra P, Liu IY.

Depression is a life-threatening psychiatric disorder and a major public health concern worldwide with an incidence of 5% and a lifetime prevalence of 15%-20%. It is related with the social disability, decreased quality of life, and a high incidence of sui...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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BACKGROUND: Limited research has been conducted to quantify the level of disability and health related quality of life (HRQoL) associated with suicidal thoughts and behaviour. The aims of the current study were to (1) describe levels of disability and HRQo...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
BACKGROUND: Suicide is one of the leading causes of death and Disability Adjusted Life Years (DALYs) worldwide. The economic, emotional and human cost of suicidal behaviour to individuals, families, communities and society makes it a serious public health ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
AbstractDuring a conflict, there is a significant disability related to common mental health problems, including depression, anxiety, and substance misuse. A self-administered questionnaire was used in a cross-sectional study that was conducted in 2016 to investigate the prevalence of and risk factors associated with psychoactive substance (PS) use among 950 teenagers in different conflict zones in the West Bank. Refugee teenagers were particularly vulnerable to PS use for different reasons, including the availability of substances, the ease of accessing them, the need to cope with problems, and social/peer pressure. The c...
Source: International Journal of Mental Health and Addiction - Category: Addiction Source Type: research
ConclusionInterventional strategies, including group interventions, brief individual interventions, longitudinal counseling, and consideration of early amputation in selected populations have proved effective in reducing negative psychological sequelae of major orthopedic trauma. Further research that determines the effects of interventions in this population is needed.
Source: HSS Journal - Category: Orthopaedics Source Type: research
This study aimed to explore the extent to which different aspects of PwMS’ activity engagement is related to pain-related illness intrusiveness, and whether certain coping and support systems mediate that relationship.Methods: Participants (N = 161) were PwMS with at least mild pain who were recruited electronically through the North American Research Committee on MS (NARCOMS). Pain-related illness intrusiveness was measured using a modified version of the Illness Intrusiveness Ratings Scale (IIRS). Activity engagement was assessed with Section III of the West Haven-Yale Multidimensional Pain Inventory (WHYMPI). ...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
November kicked off with a team of UNISON members winning a Nursing Times award for their transformative work on a secure psychiatric ward in Wales (see picture above). Then, disabled members’ conference came around and assistant general secretary Christina McAnea told delegates from across the UK that eliminating pay discrimination for workers with a disability was a key priority for the union. Members also called for mandatory disability pay gap reporting. After facing years of cuts and job losses, Northamptonshire council staff had a huge win when they were promised a 4% pay rise from April –...
Source: UNISON Health care news - Category: UK Health Authors: Tags: News 2019 Disabled Members Conference 2019 LGBT Conference 2019-LGBT general election 2019 healthcare LGBT members Source Type: news
In conclusion, Parkinson’s Disease Multimodal Complex Treatment improves motor symptoms, depression and quality of life. A more detailed selection of patients who will benefit best from this interve ntion should be examined in future studies.
Source: Journal of Neurology - Category: Neurology Source Type: research
This study therefore tailored a heuristic staging model to anxiety disorders and assessed its validity. METHODS: A clinical staging model was tailored to anxiety disorders, distinguishing nine stages of disease progression varying from subclinical stages (0, 1A, 1B) to clinical stages (2A-4B). At-risk subjects and subjects with anxiety disorders (n = 2352) from the longitudinal Netherlands Study of Depression and Anxiety were assigned to these nine stages. The model's validity was assessed by comparing baseline (construct validity) and 2-year, 4-year and 6-year follow-up (predictive validity) differences...
Source: The Australian and New Zealand Journal of Psychiatry - Category: Psychiatry Authors: Tags: Aust N Z J Psychiatry Source Type: research
Publication date: March 2020Source: Molecular Genetics and Metabolism Reports, Volume 22Author(s): Nilton Salles Rosa Neto, Judith Campos de Barros Bento, Rosa Maria Rodrigues PereiraAbstractBackground: Fabry disease (FD) is a lysosomal disease in which mutations affect the GLA gene located on the X chromosome. The defective product, the enzyme alpha-galactosidase A, causes accumulation of substrate and contributes to the disruption of cell function in several organs, with variable severity and consequent damage of tissue or organ function. Patient reported outcomes (PROs) enable patients to provide information regarding t...
Source: Molecular Genetics and Metabolism Reports - Category: Genetics & Stem Cells Source Type: research
 After receiving two chronic illness diagnosis by the age of 24, it really was no surprise that host Jackie Zimmerman also started to experience depression. Unable to tackle both, Jackie chose to focus on her physical health, letting her mental health deteriorate quickly — and dangerously. In this episode, we discuss the mind-body connection and how when your body is sick, your mind can quickly follow.   (Transcript Available Below) SUBSCRIBE &REVIEW About The Not Crazy Podcast Hosts Gabe Howard is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular bo...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Antidepressant Depression Medications Not Crazy Podcast Stress Suicide Trauma Source Type: blogs
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