Impact of hanging motionless in harness on respiratory and blood pressure reflex modulation in mountain climbers - Lanfranconi F, Ferri A, Pollastri L, Bartesaghi M, Novarina M, De Vito G, Beretta E, Tremolizzo L.

Harness hang syncope (HHS) is a risk that specifically affects safety of harness' users in mountain climbing. Aims: To evaluate individual patterns of breathing resulting from deranged cardiovas...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

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Millions of people with post-traumatic stress disorder (PTSD) — from veterans to rape survivors — have new hope because of a watershed study showing that the injection of an anesthetic to a bundle of nerves in the neck can relieve their symptoms in a clinically significant way. The treatment is known as the stellate ganglion block, or SGB. Used since 1925 for problems such as pain in the arm and shingles, it is safe and effective. In the newly released, eight-week, U.S. Army-funded clinical trial of 108 active-duty service members with PTSD, the nonprofit research institute RTI International found that patients...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Personal PTSD Research Treatment Hyper Vigilance Neuroscience Neurotransmitter Norepinephrine Posttraumatic Stress Disorder pruning Source Type: blogs
Authors: Stefano GB, Esch T, Kream RM Abstract The relaxation response derives its health benefits by reestablishing "normal" equilibria between the sympathetic and parasympathetic branches of the autonomic nervous system. Recent work suggests that this behavioral training provides positive effects on mitochondrial bioenergetics, insulin secretion, and reductions in pro-inflammatory and stress-related pathways. We have previously contended, however, that correlative associations of relaxation training with positive changes in gene expression in selected biological systems are strongly suggestive of adapti...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
ConclusionsThe atypical clinical presentation of some CGD patients can make genotype –phenotype correlation with DHR flow data challenging. Genetic testing, while useful for confirmation of diagnosis, can take several weeks, and in some patients does not provide a conclusive answer. However, NADPH-oxidase-specific protein flow assessment offers a rapid alternative to identificatio n of the underlying genetic defect in cellular subsets, and can be utilized as a reflex test to an abnormal DHR flow. Further, it can provide insight into correlation between oxidative burst relative to protein expression in granulocytes and monocytes.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 6 December 2019Source: Regulatory Toxicology and PharmacologyAuthor(s): Klaus Weber, Rüdiger Häcker, Jerold F. Hardisty, Stephen B. Harris, A. Wallace HayesAbstractBIA 10–2474 (3-(1-(cyclohexyl(methyl)carbamoyl)-1H-imidazol-4-yl)pyridine 1-oxide) is a novel fatty acid amide hydrolase (FAAH) inhibitor developed by BIAL for the treatment of medical conditions which would benefit from enhanced levels of endogenous anandamide (AEA) such as pain disorders. During a Phase I clinical trial one subject died after receiving BIA 10–2474 and others displayed neurological signs....
Source: Regulatory Toxicology and Pharmacology - Category: Toxicology Source Type: research
No abstract available
Source: Journal of Cardiovascular Nursing - Category: Nursing Tags: DEPARTMENTS: Letter to the Editor Source Type: research
PMID: 31804247 [PubMed - in process]
Source: The Journal of Cardiovascular Nursing - Category: Nursing Authors: Tags: J Cardiovasc Nurs Source Type: research
AbstractThe innervation of the long head of the biceps tendon (LHBT) is not sufficiently documented. This is a drawback since pathologies of the LHBT are a major source of shoulder pain. Thus, the study aimed to characterize structurally and molecularly nervous elements of the LHBT. The proximal part of 11 LHBTs was harvested intraoperatively. There were 8 female and 3 male specimens. Age ranged from 66 to 86  years. For structural analyses, nervous elements were viewed in the transmission electron microscope. For molecular characterization, we used general neuronal markers including antibodies against neurofilament a...
Source: Cell and Tissue Research - Category: Cytology Source Type: research
ConclusionsThese results showed a cardiac parasympathetic dominance to the same extent, underpinned by a similar arterial baroreflex activation during WI and HDT as well as control SP. Future studies may address their association with cold or hyperoxia to assess their ability to replicate autonomic cardiovascular adaptations to microgravity, swimming or scuba diving.
Source: European Journal of Applied Physiology - Category: Physiology Source Type: research
Conclusions: The results indicate no difference in graft survival between PK and EK for ICE syndrome. Graft survival in ICE syndrome is intermediate between that of FED and PBK.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: DM suturing can reattach DM, especially in moderate to severe, recurrent DMD with fewer postoperative complications and thereby reduce the need for corneal transplantation.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
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