Low Plasma Sodium Concentration Predicts Perforated Acute Appendicitis in Children: A Prospective Diagnostic Accuracy Study

Conclusion In children with AA, there is a strong association between low plasma sodium concentration and perforation, a novel and not previously described finding. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - Category: Surgery Authors: Tags: Original Article Source Type: research

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CONCLUSIONS: Appendiceal perforation may be accompanied with elevated serum bilirubin level. Assessment of bilirubin levels must be a part of the initial evaluation of a suspected appendicitis in the emergency room. KEY WORDS: Acute appendicitis, Gangrenous appendicitis, Perforated appendicitis, Serum bilirubin, Total Hyperbilirubinemia. PMID: 31814597 [PubMed - in process]
Source: Annali Italiani di Chirurgia - Category: Surgery Tags: Ann Ital Chir Source Type: research
ConclusionsmFOLFOX6 might be an effective and tolerable treatment option for patients with unresectable PMP. To our knowledge, this is the first case series of mFOLFOX6 in patients with unresectable PMP and the first case series of systemic chemotherapy for Asian patients with unresectable PMP.
Source: International Journal of Clinical Oncology - Category: Cancer & Oncology Source Type: research
This study aimed to determine the effects of interval appendectomy from the perspective of long-term follow-up.MethodsA retrospective review of patients with complicated appendicitis between 2010 and 2017 was performed. The medical records of 471 patients with initial non-operative therapy and 377 patients treated with emergency appendectomy who served as controls were reviewed. Propensity score matching was performed to adjust for any potential selection bias in the two strategies. A comparison of the clinical outcomes, including short- and long-term postoperative complications, was conducted in the 348 matched patients.R...
Source: European Journal of Trauma and Emergency Surgery - Category: Emergency Medicine Source Type: research
ConclusionFactors such as elderly age, CT features such as larger appendicular diameter, appendicular wall calcifications along with sigmoid colon, and cecal calcifications, signs of perforation or abscess are characteristic for early recognition of SAA.
Source: Japanese Journal of Radiology - Category: Radiology Source Type: research
AbstractBackgroundAcute appendicitis is one of the most common abdominal emergencies. Despite all improvements in diagnostic techniques, there are still ongoing problems as proper diagnosis, misdiagnosis and perforated appendicitis. The aim of this study is to demonstrate the clinical value of IMA in patients with appendicitis and to determine the accurate diagnosis of appendicitis in clinically suspected patients.MethodsPediatric patients with acute abdominal pain who had the Pediatric Appendicitis Score (PAS)  ≥ 7 (n = 109) and a control group of 35 patients were included in this prospectiv...
Source: World Journal of Surgery - Category: Surgery Source Type: research
ConclusionAmong patients with appendicitis, there are relevant risk factors predicting appendiceal tumors, especially age and appendiceal diameter in sonography. But the identified risk factors have a low sensitivity and specificity, so obtaining a confident preoperative diagnosis is challenging.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research
Due to their fundamentally different biology, archaea are consistently overlooked in conventional microbiome surveys. Using amplicon sequencing, we evaluated methodological set-ups to detect archaea in samples from five different body sites: respiratory tract (nasal cavity), digestive tract (mouth, appendix, and stool) and skin. With optimized protocols, the detection of archaeal ribosomal sequence variants (RSVs) was increased from one (found in currently used, so-called “universal” approach) to 81 RSVs in a representative sample set. The results from this extensive primer-evaluation led to the identification ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
There’s been a lot of good news recently for people who experience migraines. In 2018, the U.S. Food and Drug Administration approved three drugs aimed to prevent migraines from occurring, and, over time, help to make them less frequent and less intense. Treating migraine pain while an attack is underway, however, is a bigger challenge. Triptans are the most popular medications used for this purpose, but they don’t work for everyone. In a study published in the New England Journal of Medicine, researchers report encouraging results with a promising class of oral drugs called gepants, which are meant to be taken...
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Scientists at the University of Birmingham studied 274 hospitals and found those in the UK have the highest rates of unnecessary appendectomies in which the patient's organ turned out to be healthy.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
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