Meaningful and feasible composite clinical worsening definitions in paediatric pulmonary arterial hypertension: An analysis of the TOPP registry

Composite clinical worsening (cCW) outcomes might allow measurement of disease progression in paediatric pulmonary arterial hypertension (PAH). This TOPP registry analysis investigated three cCW outcomes and their predictive strength for lung transplantation/death.

Source: International Journal of Cardiology - April 24, 2019 Category: Cardiology Authors: Maurice Beghetti, Monika Brand, Rolf M.F. Berger, Tilman Humpl, Jeremy G. Wheeler, D. Dunbar Ivy, Damien Bonnet, TOPP investigators Source Type: research