Psychiatric Comorbidity in Neurological Disorders: Towards a Multidisciplinary Approach to Illness Management in the United Arab Emirates

Conclusion: Our results indicate similar prevalence rates of comorbid psychiatric symptoms to studies carried out in the Middle East and North Africa (MENA) region and relatively high attendance and referral rates to psychiatric services.Implications: The results shed light on the clinical profile of patients in this region and support the need for integrated collaborative medical services. Moreover, findings have important implications for health care policies pertaining to resource distribution and funding.IntroductionMedical care has traditionally been dominated by a separation between disciplines catering to physiological symptoms versus those catering to psychological symptoms (1). Emerging research points to psychiatric comorbidity in the primary care setting and in specialized services, especially with chronic conditions like cardiovascular disease and diabetes. Among psychiatric comorbidities, depression and anxiety disorders are the most prevalent and have been found to hinder treatment response, increasing disability and reducing functional outcome (2–6). Given the shared etiological processes between neurological disorders and psychiatric disorders, reports of 50% prevalence rates of depression and anxiety among neurology patients are not surprising (7). Despite ample evidence on comorbidity, the provision of psychiatric intervention for such patients remains lacking.Several epidemiological studies have attempted to quantify psychiatric comorbidity in primary...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research

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Date: Monday, 10 28, 2019; Speaker: Xiangbo Ruan, Regulation of systemic lipid metabolism by human lncRNAs, The Cao group, CB, NHLBI; Ranganath Muniyappa, Hyperuricemia in insulin resistance, DEOB, NIDDK; Building: Building 10 (Clinical Center); Solarium Conference Room 9S233 (old Bunim Room)
Source: NIH Calendar of Events - Category: American Health Source Type: events
Publication date: Available online 21 October 2019Source: Autoimmunity ReviewsAuthor(s): Piercarlo Sarzi-Puttini, Jacob Ablin, Adva Trabelsi, Mary-Ann Fitzcharles, Daniela Marotto, Winfried HäuserAbstractMedical cannabis is being increasingly used in the treatment of rheumatic diseases because, despite the paucity of evidence regarding its safety and efficacy, a growing number of countries are legalising its use for medical purposes in response to social pressure. Cannabinoids may be useful in the management of rheumatic disorders for two broad reasons: their anti-inflammatory and immunomodulatory activity, and their ...
Source: Autoimmunity Reviews - Category: Allergy & Immunology Source Type: research
This article highlights the role of nuclear medicine in standardizing the diagnostic approach in patients with infectious/inflammatory diseases, in particular in peripheral osteomyelitis, septic arthritis, prosthetic joint infections, infected diabetic foot and spinal infections. The authors reveal the role of the most common radionuclides tests, with their advantages and clinical indications, to achieve an adequate diagnosis of infection and inflammation.ResumenLas enfermedades inflamatorias e infecciosas osteoarticulares pueden tener graves consecuencias para el paciente si no se diagnostican a tiempo. En las últi...
Source: Revista Espanola de Medicina Nuclear e Imagen Molecular - Category: Nuclear Medicine Source Type: research
Publication date: Available online 21 October 2019Source: Stem Cell ResearchAuthor(s): T.A. Shnaider, I.E. Pristyazhnyuk, A.G. Menzorov, N.M. Matveeva, A.A Khabarova, N.A. Skryabin, A.A. Kashevarova, M.E. Lopatkina, L.P. Nazarenko, I.N. Lebedev, O.L. SerovAbstractThe human induced pluripotent stem cell (iPSC) lines, ICGi009-A, ICGi009-B, ICGi013-A and ICGi013-B, were generated from skin fibroblasts of two siblings with intellectual disability. Both patients were carriers of CNTN6 gene microdeletion(Kashevarova et al., 2014). iPSC lines have normal karyotype, express pluripotency markers, are able to differentiate in vitro ...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
Publication date: Available online 21 October 2019Source: Stem Cell ResearchAuthor(s): Haiyan Zhang, Yanyan Ma, Shujuan Yu, Xiaomeng Yang, Yue Li, Jingyun Guan, Rui Dong, Zhongtao Gai, Yi LiuAbstractWe established an induced pluripotent stem cell (iPSC) line (SDQLCHi010-A) from peripheral blood mononuclear cells isolated from a 4-year-old boy with optic nerve malformation and intellectual disability carrying a heterozygous mutation (c.220A>G (p.S74G)) in PAX6 gene. Non-integrating episomal vectors containing OCT4, SOX2, KLF4, BCL-XL and MYC were used for reprogramming. The established iPSC line showed normal karyotype, ...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
The objectives of this study were to determine, in a real-life setting, the global effectiveness of an emulsion with antiseborrheic, keratolytic and anti-Propionibacterium acnes activities as an adjunct to anti-acne therapy, and to evaluate the effect of the product on acne severity, noninflammatory and inflammatory lesions, hyperseborrhea, skin irritation and patient quality of life (QoL). Tolerance of the product was also assessed. Patients and methods: This international observational study involved 3960 patients aged 12 years and over with mild-to-moderate acne. The conventional acne prescriptions for these patient...
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Tags: Clin Cosmet Investig Dermatol Source Type: research
Publication date: 1 January 2020Source: Materials Letters, Volume 258Author(s): Akihiko Ito, Yuki MorishitaAbstractWe demonstrated selective self-oriented growth of triclinic tungsten trioxide (δ-WO3) films with (2 0 0), (0 0 2), and (0 2 0) orientations on polycrystalline AlN substrate using metal-organic chemical vapor deposition (MOCVD) by changing W(CO)6 vaporization temperature. At deposition temperatures of 1123–1223 K and total chamber pressure of 0.2 kPa, the orientation of δ-WO3 films changed from (2 0 0) to (0 0 2) to (0 2 0) to (0 0 2) plane as the increase of W(...
Source: Materials Letters - Category: Materials Science Source Type: research
Publication date: Available online 21 October 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Xinxu Yuan, Owais M. Bhat, Hannah Lohner, Yang Zhang, Pin-Lan LiAbstractExosomes have been demonstrated to be one of the mechanisms mediating the release of intracellular signaling molecules to conduct cell-to-cell communication. However, it remains unknown whether and how exosomes mediate the release of NOD-like receptor pyrin domain 3 (NLRP3) inflammasome products such as interleukin-1 beta (IL-1β) from endothelial cells. The present study hypothesized that lysosomal acid cer...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - Category: Lipidology Source Type: research
Pitch Black is a binaural audio game, entirely accessible to blind and partially sighted people, featuring a fully traversable 3D environment with compelling story, created entirely through sonic environments
Source: Disabled World - Category: Disability Tags: Games - Gaming Source Type: news
This study tested the specificity of associations between childhood multi-trajectories of shyness, anxiety and depression symptoms and adolescent social phobia, generalized anxiety disorder (GAD) and depression, as well as functional impairment. A population sample of 1596 singletons was followed over 15 years. Mothers rated child shyness, anxiety and depression between 1½ and 8 years-old. Adolescents self-reported symptoms of social phobia, GAD and depression at 15 years-old. Multi-trajectories of childhood internalizing symptoms showed developmental heterogeneity. Controlling for perinatal risk factors, low ...
Source: Journal of Applied Developmental Psychology - Category: Child Development Source Type: research
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