Endoscopic response to tumor necrosis factor inhibitors predicts long term benefits in Crohn's disease.

CONCLUSION: Clinical and biomarker data are not useful predictors of response to TNF-α inhibitors in CD, whereas ER to induction therapy, defined as 80% reduction in global CDEIS, is a robust predictor of long-term MH. Achievement of this endoscopic endpoint may be considered as a therapeutic target for anti-TNF-α therapy.
PMID: 31011260 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - April 13, 2019 Category: Gastroenterology Authors: Alfaro I, Masamunt MC, Planell N, López-García A, Castro J, Gallego M, Barastegui R, Giner A, Vara A, Salas A, Ricart E, Panés J, Ordás I Tags: World J Gastroenterol Source Type: research