The WATER Study: a Review

This study compared the efficacy and safety of Aquablation to transurethral resection of the prostate (TURP) for the treatment of male lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).Recent FindingsThe WATER study compared Aquablation using the AquaBeam system to the current gold standard, TURP. It demonstrated that Aquablation was non-inferior to TURP when comparing the primary efficacy study endpoint of reduction in International Prostate Symptom Score at 6-month follow-up. Additionally, it proved superior for the primary safety endpoints at 3 and 6  months.SummaryAquablation has been shown to provide non-inferior symptom relief when compared with TURP. Additionally, it demonstrated a significantly superior safety profile and lower risk of sexual dysfunction. Ongoing trials including the Open WATER study and WATER 2 study are completing follow-up in 2019 with the promise of determining the safety and efficacy of Aquablation in larger prostates (80 –150 g).
Source: Current Bladder Dysfunction Reports - Category: Urology & Nephrology Source Type: research