Virtual reality engages patients more than CT, booklets

Patients with an abdominal aortic aneurysm were more engaged and had a better...Read more on AuntMinnie.comRelated Reading: 4 practical applications of VR, AR in radiology SIR: Virtual reality beats fluoroscopy for catheter placement VR, AR elevate radiologists' value in future of medicine Virtual reality may help plan, guide glioma resection VR software may increase MRI segmentation efficiency
Source: Headlines - Category: Radiology Source Type: news

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CONCLUSIONS: In aggregate, our results suggest that increased expression of miR-106a promotes VSMC cell apoptosis and down-regulates TIMP-2 through directly targeting its 3'-UTR, which in turn restores MMP production and ultimately accelerates ECM degradation. Therefore miR-106a is proposed to play a crucial role in AAA development and this will provide an update on the understanding of the clinical value of miRNAs as novel therapeutic targets for the treatment of this disease. PMID: 32767336 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research
Publication date: Available online 13 August 2020Source: Acta Pharmaceutica Sinica BAuthor(s): Jinyang Li, Jiasheng Lu, Haiyan Guo, Jianfen Zhou, Songli Wang, Kuan Jiang, Zhilan Chai, Shengyu Yao, Xiaoyi Wang, Linwei Lu, Cao Xie, Yi Chen, Weiyue Lu
Source: Acta Pharmaceutica Sinica B - Category: Cancer & Oncology Source Type: research
Source: OncoTargets and Therapy - Category: Cancer & Oncology Tags: OncoTargets and Therapy Source Type: research
CONCLUSIONS These findings demonstrated that NORAD silencing suppressed proliferation, invasion, and migration and boosted apoptosis of glioma cells via downregulating the AKR1B1 expression, which may provide a potential therapeutic target for glioma treatment. PMID: 32778640 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
This study indicates that CD73 knockdown using a nanotechnological approach to perform nasal delivery of siRNA-CD73 to CNS can potentially regulate the glioblastoma immune microenvironment and delay tumor growth by inducing apoptosis.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research
Conclusion: GB/PNC is extremely rare tumors. Given its low prevalence, there are no studies that refer to the macroscopic characteristics of the tumor as well as evidence of the effectiveness of adjuvant treatment. Fluorescence-guided resection with 5-ALA is the surgical treatment of choice in surgery for high-grade gliomas; however, in GB/PNC, it may not be as useful since PNC may have less fluorescent marker uptake and be more dimly visualized when excited by light using the surgical microscope. PMID: 32754353 [PubMed]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research
Drug delivery is one of the major challenges in the treatment of central nervous system disorders. The brain needs to be protected from harmful agents, which are done by the capillary network, the so-called blood–brain barrier (BBB). This protective guard also prevents the delivery of therapeutic agents to the brain and limits the effectiveness of treatment. For this reason, various strategies have been explored by scientists for overcoming the BBB from disruption of the BBB to targeted delivery of nanoparticles (NPs) and cells and immunotherapy. In this review, different promising brain drug delivery strategies incl...
Source: IET Nanobiotechnology - Category: Nanotechnology Source Type: research
Publication date: September 2020Source: Journal of Clinical Neuroscience, Volume 79Author(s): Ryan P. Hamer, Swati Jain, Colin Teo, Will Ne-Hooi Loh, Hui-Minn Chan, Tseng T. Yeo, Kejia Teo
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 7 August 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Weimin Yu, Li Xiao, Yumei Que, Siqi Li, Lili Chen, Pingping Hu, Rui Xiong, Francesca Seta, Hao Chen, Xiaoyong Tong
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
Publication date: Available online 11 August 2020Source: International Journal of Surgery Case ReportsAuthor(s): Ettore Dinoto, Felice Pecoraro, Arduino Farina, Alessia Viscardi, Guido Bajardi
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
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