How Low Do We Go (in the Post-SPRINT Era)?

Publication date: March 2019Source: Advances in Chronic Kidney Disease, Volume 26, Issue 2Author(s): Anna Burgner, Julia B. LewisHypertension is frequently both a cause and complication of CKD. The optimal blood pressure target in CKD has been of hot debate over the decades with little data to inform the goals. Here, we review the data from the Systolic Blood Pressure Intervention Trial (SPRINT), Modification of Diet in Renal Disease (MDRD), African American Study of Kidney Disease and Hypertension (AASK), Ramipril Efficacy in Nephropathy-2 (REIN-2), and Action to Control Cardiovascular Risk in Diabetes (ACCORD) trials to use the available evidence to better inform what blood pressure goal should be recommended in patients with CKD and to answer the question “How low should we go?”.
Source: Advances in Chronic Kidney Disease - Category: Urology & Nephrology Source Type: research