Polyp size of 1  cm is insufficient to discriminate neoplastic and non-neoplastic gallbladder polyps

This study assessed a national cohort of histopathologically proven gallbladder polyps to distinguish neoplastic from non-neoplastic polyps.MethodsPALGA, the nationwide network and registry of histo- and cytopathology, was searched to identify all histopathologically proven gallbladder polyps between 2003 and 2013. All polyps and (focal) wall thickenings  >  5 mm were included, and classified as neoplastic or non-neoplastic. Polyp subtype, size, distribution, presentation as wall thickening or protruding polyp, and presence of gallstones were assessed for neoplastic and non-neoplastic polyps. A decision tree to distinguish neoplastic and non-neoplas tic polyps was made and diagnostic accuracy of 1 cm surgical threshold was calculated.ResultsA total of 2085 out of 220,612 cholecystectomies contained a polyp (0.9%). Of these polyps, 56.4% were neoplastic (40.1% premalignant, 59.9% malignant) and 43.6% non-neoplastic (41.5% cholesterol polyp, 37.0% adenomyomatosis, 21.5% other). Polyp size, distribution, and presence of gallstones were reported in 1059, 1739 and 1143 pathology reports, respectively. Neoplastic polyps differed from non-neoplastic polyps in size (18.1  mm vs 7.5 mm,p 
Source: Surgical Endoscopy - Category: Surgery Source Type: research

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Publication date: February 2020Source: Food Research International, Volume 128Author(s): Graziela Bragueto Escher, Mariza Boscacci Marques, Mariana Araújo Vieira do Carmo, Luciana Azevedo, Marianna Miranda Furtado, Anderson S. Sant'Ana, Marcia Cristina da Silva, Maria Inês Genovese, Mingchun Wen, Liang Zhang, Won Young Oh, Fereidoon Shahidi, Neiva Deliberali Rosso, Daniel GranatoAbstractThe purpose of this study was to use a statistical approach to optimise the experimental conditions regarding the extraction of bioactive compounds, and to analyse the in vitro functional properties of crude lyophilized extract...
Source: Food Research International - Category: Food Science Source Type: research
Publication date: Available online 19 November 2019Source: Food ChemistryAuthor(s): Shaimaa Selim, Eman HusseinAbstractThe effect of including sugar beet pulp (SBP) in laying hen diets on performance, egg quality, blood chemistry and egg lipid peroxidation was studied. A total of 200 laying hens were randomly assigned into 4 groups and were offered diets containing SBP at the level of 0%, 3%, 5% and 7%. The dietary inclusion of SBP linearly (P
Source: Food Chemistry - Category: Food Science Source Type: research
Publication date: Available online 18 November 2019Source: Saudi Journal of Biological SciencesAuthor(s): V. Duraipandiyan, R. Balamurugan, Naif Abdullah Al-Dhabi, T. William Raja, P. Ganesan, B. Ahilan, M. Valan Arasu, S. Ignacimuthu, Galal Ali EsmailAbstractBorassus flabellifer L. is a tall palm traditionally used for its stimulating, diuretic and anti-inflammatory activities; it is rich in fibers and various pharmacologically important secondary metabolites. The present study was undertaken to evaluate the antidiabetic effects of Borassus flabellifer fruit methanol extract (BF-M) on diabetic rats induced with High Fat D...
Source: Saudi Journal of Biological Sciences - Category: Biology Source Type: research
Authors: Şener YZ, Okşul M PMID: 31738654 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
Conditions:   Esophagogastroduodenoscopy;   Deep Sedation;   Cognition Disorders Interventions:   Drug: Propofol;   Device: endoscopy Sponsor:   Shanghai Jiao Tong University School of Medicine Terminated
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Cosmeri Rizzato1, Javier Torres2, Elena Kasamatsu3, Margarita Camorlinga-Ponce2, Maria Mercedes Bravo4, Federico Canzian5 and Ikuko Kato6* 1Department of Translation Research and of New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy 2Unidad de Investigación en Enfermedades Infecciosas, Unidades Médicas de Alta Especialidad Pediatría, Instituto Mexicano del Seguro Social, Mexico City, Mexico 3Instituto de Investigaciones en Ciencias de la Salud, National University of Asunción, Asunción, Paraguay 4Grupo de Investigación en Biología del C&aacut...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Abstract Acute pancreatitis is an inflammatory condition of the pancreas manifesting with abdominal pain and elevated serum levels of pancreatic enzymes. Gallstones and chronic alcohol use are the most commonly described causes. A less studied cause is cholesterolosis, gallbladder polyps that cause mechanical obstruction of the sphincter of Oddi. Here, we present the case of a 55-year-old woman who presented with acute pancreatitis and was found to have cholesterol polyps in her gallbladder with no evidence of gallstones. The patient underwent cholecystectomy with complete resolution of her symptoms. PMID: 29904299 [PubMed]
Source: Baylor University Medical Center Proceedings - Category: Universities & Medical Training Authors: Tags: Proc (Bayl Univ Med Cent) Source Type: research
This study aimed to analyze clinic and pathologic characteristics of 1446 USG-detected GPs, identify predictive factors for cholesterol lesions and malignancy, and provide comments and recommendations on specific aspects of GPs.MethodsWe retrospectively analyzed clinic files of 1446 patients who underwent cholecystectomy for USG-detected GPs between 2008 and 2015 in Gallbladder Diseases Center, East Hospital of Tongji University.ResultsFor the 1446 patients, the F: M ratio and the mean age were 1.06: 1 and 45  years, and most of them were asymptotic (80.3%) and had multiple polyps (62.5%). All the 1446 GPs were classi...
Source: Journal of Gastrointestinal Surgery - Category: Surgery Source Type: research
CONCLUSIONS: The mucin genes with the highest expression levels in gallbladder tissue in cholesterol-associated diseases were MUC3 and MUC5B. Cholesterol stones and gallbladder infections were associated with increased MUC3 and MUC5B expression. PMID: 27563024 [PubMed - in process]
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
CONCLUSIONS: Age, female sex, BMI, non-HDL cholesterol, and polyps are independent determinants for gallstone formation. Incident gallstones and the metabolic syndrome share common risk factors. More studies are needed for further exploration. PMID: 27232657 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
More News: Cancer & Oncology | Cholecystectomy | Cholesterol | Endoscopy | Gallstones | Pathology | Polyp Resection | Polyps | Study | Surgery