Acujoint™, a high efficient formulation with natural bioactives, exerts potent anti-arthritis effects in human osteoarthritis - A randomized clinical study

Publication date: Available online 23 April 2019Source: Journal of Herbal MedicineAuthor(s): Augustine Amalraj, Joby Jacob, Karthik Varma, Ajaikumar B. Kunnumakkara, Chandradhara Divya, Sreeraj GopiAbstractThe aim of the study was to evaluate the efficacy and safety of Acujoint™ - a supplement for articular cartilage degradation- in the treatment of patients with Osteoarthritis (OA) by comparing it with glucosamine and chondroitin formulation, which is a popular supplement used to treat OA. Acujoint™ is a health supplement prepared with extracts of 3-O-acetyl-11-keto-β-boswellic acid from Boswellia serrata, β-Caryophyllene from Piper nigrum, aqueous extract of Kaempferia galangal and Cureit™ - a bioavailable curcumin formulation- in a fixed ratio based on complete natural matrix, which has been used to treat osteoarthritis. A randomized, double blind, active controlled, single centre, clinical study was carried out using Acujoint™ during 90 days of treatment in 24 patients (1:1 ratio) with symptoms of moderate to mild OA along with combination of Glucosamine (1500 mg) and Chondroitin (1200 mg). The study shows that Acujoint™ can provide significant improvement in relieving the symptoms and the pain associated with active OA between the groups as well as within the groups. Active OA patients, who received Acujoint™ at 250 mg per day for a treatment period of 90 days, reported statistically significant changes/decreases in their clinical symptoms and pain. T...
Source: Journal of Herbal Medicine - Category: Complementary Medicine Source Type: research