Adaptation of the Human Gut Microbiota Metabolic Network During the First Year After Birth
This study was approved by the Ethics Committee of the Center for Public Health Research (CSISP), Valencia, Spain. All women participating in the study read and signed forms of informed consent specifically approved for this project by the Ethics Committee.
Author Contributions
MF, JR-H, and FP conceived this study. IA and AF carried out the computational implementation. SP-B performed the metabolomic experiments. YV generated and processed metagenomic data and collected food frequency questionnaires. All authors wrote, read, and approved the manuscript.
Funding
IA was supported by a Basque Government predoctoral grant (PRE_2017_2_0028). SP-B was supported by a Spanish Government predoctoral grant (FPU14/01192). This manuscript will form part of the doctoral thesis of SP-B conducted within the context of the “Nutrition and Food Sciences Programme” at the University of Granada. This work was supported by the EU Project STANCE4HEALTH (contract number 816303) and the Ministry of Economy and Competitiveness of Spain (BIO2016-77998-R, SAF2009-13032-C02-02, CSD2009-00006 and SAF2012-31187).
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Acknowledgments
We thank Ines Thiele and Almut Heinken for providing us with the metabolic reconstruction presented in Heinken and Thiele (2015).
Supplementary Material
T...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
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