Characterizing trunk muscle activations during simulated low-speed rear impact collisions.

CONCLUSIONS: Results from this investigation demonstrate that during an unanticipated low-speed rear-end collision, the peak activation of muscles in the lumbar spine are low in magnitude. As such, muscle activation likely has minimal contribution to the internal joint loads that are experienced in the lumbar intervertebral joints during low-speed rear impact collisions. These findings justify the use of simplified joint models in estimating the joint loads in the lumbar spine during low-speed rear impact collisions and support the application of cadaveric and anthropomorphic test device (ATD) testing in understanding the resultant joint loads in the lumbar spine associated with rear-end collisions. PMID: 31013170 [PubMed - as supplied by publisher]
Source: Traffic Injury Prevention - Category: Accident Prevention Authors: Tags: Traffic Inj Prev Source Type: research

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We present the case of a woman with DBS as a treatment for PD, safely treated with ECT for a psychotic depression. Depression severity and motor changes were evaluated on a weekly basis using the Montgomery-Åsberg Depression Rating Scale and the Unified Parkinson's Disease Rating Scale. During the course of ECT, the Montgomery-Åsberg Depression Rating Scale score declined from 34 to 13, and the Unified Parkinson's Disease Rating Scale motor score from 44 to 12 with positive impact on rigidity. Considering the positive impact of ECT on the motor function in our patient, new research should look into ECT as an au...
Source: The Journal of ECT - Category: Psychiatry Tags: Case Reports Source Type: research
New MRI technique reveals iron accumulations that could lead to Parkinson ’s dementia prediction.
Source: Diagnostic Imaging - Category: Radiology Authors: Tags: Brain MRI Dementia Parkinsons Disease Source Type: news
Publication date: Available online 20 February 2020Source: Journal of Electroanalytical ChemistryAuthor(s): Ya Ma, Qiong Hu, Cheng Liu, Lishi WangAbstractIn this manuscript, a nanospherical conjugated microporous polymer (CMP) was synthesized. This material together with graphene nanosheets (GS) was used as electrode modification materials to construct a molecularly imprinted electrochemical sensor for high sensitivity detection of α-Synuclein (α-Syn). The MIP sensor was synthesized by electropolymerization pyrrole and characterized by scanning electron microscopy (SEM), cyclic voltammetry (CV) and differential...
Source: Journal of Electroanalytical Chemistry - Category: Chemistry Source Type: research
Conditions:   Dystonia Disorder;   Parkinson Disease Interventions:   Drug: Botulinum toxin type A;   Drug: Placebo Sponsors:   University of Calgary;   Allergan Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Neural implants may provide treatment options for a wide variety of ailments, including Parkinson’s and epilepsy, but such devices have to work for long periods of time in a very difficult environment inside the cranium. One challenge is provid...
Source: Medgadget - Category: Medical Devices Authors: Tags: Materials Neurology Neurosurgery Source Type: blogs
BACKGROUND: Nocturnal hypokinesia commonly affects Parkinson's disease (PD) patients, manifesting primarily as an impaired ability to turn in bed and sleeping in specific positions, such as prone that potentially poses the risk of positional asphyxia. ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Conditions:   Dystonia Disorder;   Parkinson Disease Interventions:   Drug: Botulinum toxin type A;   Drug: Placebo Sponsors:   University of Calgary;   Allergan Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 19 February 2020Source: International Journal of PharmaceuticsAuthor(s): Subrat K. Bhattamisra, Angeline S. Tzeyung, Lim Wen Xi, Nurul Hasyanazifa Safian, Hira Choudhury, Lim Wei Meng, Naiyer Shahzad, Nabil A. Alhakamy, Md khalid Anwer, Ammu K. Radhakrishnan, Shadab MdAbstractRotigotine, a non-ergoline dopamine agonist, has been shown to be highly effective for the treatment of Parkinson's disease (PD). However, despite its therapeutic potential, its’ clinical applications were hindered due to low aqueous solubility, first-pass metabolism and low bioavailability. Therefore, we devel...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
THURSDAY, Feb. 20, 2020 -- Love to cross-country ski? Well, all those days spent striding across the snow-covered wilderness may do more than keep you in great physical shape. Swedish researchers report that very fit long-distance skiers were about...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
No abstract available
Source: Neurology Today - Category: Neurology Tags: In the Pipeline Source Type: research
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