Medical News Today: Is this chest pain from GERD or a heart attack?

Both heartburn and heart attacks can cause pain in the center of the chest. Heartburn is a symptom of acid reflux and gastroesophageal reflux disease (GERD). As a heart attack is a medical emergency, being able to tell the difference between heartburn and cardiac chest pain is crucial. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Acid Reflux / GERD Source Type: news

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This study attempted to see the role of MIAT in a cell model of osteoarthritis (OA). ATDC5 cells were subjected to lipopolysaccharides (LPS) to mimic a cell model of OA. The effects of MIAT on the model were tested by performing CCK-8 assay, flow cytometry, qRT-PCR, western blot and ELISA. The downstream miRNA and signalling pathways were studied by utilizing qRT-PCR and western blot. Transfection of ATDC5 cells with the shRNA specific against MIAT significantly attenuated LPS-evoked apoptosis and cytokines release. At the meantime, the viability loss and the cleavage of caspases were ameliorated as well. MIAT overexpresse...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Abstract BACKGROUND: Necroptosis plays an important role in human atherosclerosis and atheroma development. Since receptor interacting protein kinase-3 (RIP3) acts as a key mediator of necroptosis, this study aimed to explore its relationship between plasma RIP3 levels and coronary artery disease (CAD) and discover a potential new biomarker for screening CAD subtypes and severity. METHODS: A total of 318 patients with CAD who had coronary angiography and 166 controls in Peking Union Medical College Hospital from September 2017 to January 2018 were enrolled in this study. Patients with CAD were divided into th...
Source: Chinese Medical Journal - Category: General Medicine Authors: Tags: Chin Med J (Engl) Source Type: research
Publication date: Available online 18 June 2019Source: Neuroscience LettersAuthor(s): Fabiano V. Costa, Julia Canzian, Flavia V. Stefanello, Allan V. Kalueff, Denis B. RosembergAbstractThe ability to detect noxious stimuli is essential to survival. However, pathological pain is maladaptive and severely debilitating. Endogenous and exogenous opioids modulate pain responses via opioid receptors, reducing pain sensibility. Due to the high genetic and physiological similarities to rodents and humans, the zebrafish is a valuable tool to assess pain responses and the underlying mechanisms involved in nociception. Although morphi...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 18 June 2019Source: NeuroscienceAuthor(s): Kimberly Gómez, Alejandro Sandoval, Paulino Barragán-Iglesias, Vinicio Granados-Soto, Rodolfo Delgado-Lezama, Ricardo Felix, Ricardo González-RamírezAbstractHigh voltage-activated (HVA) Ca2+ (CaV) channels are oligomeric complexes formed by an ion-conducting main subunit (Cavα1) and at least two auxiliary subunits (Cavβ and CaVα2δ). It has been reported that the expression of CaVα2δ1 increases in the dorsal root ganglia (DRGs) of animals with mechanical allodynia, and that the transcr...
Source: Neuroscience - Category: Neuroscience Source Type: research
A previously healthy, well-appearing 42-year-old female living in a modern, high-rise apartment in downtown Los Angeles calls 9-1-1 at 5:30 am complaining of worsening of a burning, epigastric pain she had been experiencing for the last three days. She reports associated nausea and non-bloody, non-bilious vomiting, and that she couldn’t manage to get comfortable in bed until she finally decided to call for help at daybreak. During her 9-1-1 call, she reports “pain, like heartburn, that just woke me up again and I had to throw up, … and then I was sweating so much.” Using the Los Angeles Tiered Disp...
Source: JEMS Special Topics - Category: Emergency Medicine Authors: Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news
MedTech Strategist working together with The Medical Alley Association for the very first time brought their premier innovation summit to Minnesota, a place now considered by many to be the global epicenter of health innovation and care. Over the two...
Source: Medgadget - Category: Medical Devices Authors: Tags: Exclusive Source Type: blogs
I’ve heard this many times over the years: “I allow myself one cheat day a week.” Or “I allow myself a cheat every Friday night.” Or “I have a couple of slices of pizza every Saturday.” Or the comments from naysayers such as “A little bit can’t hurt” or “Everything in moderation.” I urge everyone to never cheat on the Wheat Belly Lifestyle. – Tweet this! It’s not because I’m a control freak or because I like to make arbitrary rules. There are many reasons to never allow yourself such a cheat. This has nothing to do with the few calori...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Diabetes Dr. Davis Grain Free Lifestyle Grains Inflammation News & Updates Wheat Belly Wheat Belly Total Health Wheat-Free Lifestyle Weight Loss Source Type: blogs
I’ve heard this many times over the years: “I allow myself one cheat day a week.” Or “I allow myself a cheat every Friday night.” Or “I have a couple of slices of pizza every Saturday.” Or the comments from naysayers such as “A little bit can’t hurt” or “Everything in moderation.” I urge everyone to never cheat. On the Wheat Belly Lifestyle. – Tweet this! It’s not because I’m a control freak or because I like to make arbitrary rules. There are many reasons to never allow yourself such a cheat. This has nothing to do with the few calor...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates Source Type: blogs
Remember Matthew? I previously shared his story and photos, including his 80-pound weight loss and change in cholesterol values. But there is much more to his story that he has been sharing on the Official Wheat Belly Facebook page. Because the changes he described were so extensive, I’ve collected his comments here. Put together, Matthew’s health transformation is nothing short of astounding. He previously told us that hypertension and pre-diabetes have reversed with now normal blood pressure and blood sugars. But just read on and see how much more happened. Matthew’s experience is a terrific example of ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Success Stories acid reflux allergy asthma cholesterol cramps gerd gluten grains heartburn IBS indigestion spastic colon Weight Loss Source Type: blogs
I’ve heard this many times over the years: “I allow myself one cheat day a week.” Or “I allow myself a cheat every Friday night.” Or “I have a couple of slices of pizza every Saturday.” Or the comments from naysayers such as “A little bit can’t hurt” or “Everything in moderation.” I urge everyone to never cheat, however. But it’s not because I’m a control freak or because I like to make arbitrary rules. There are many reasons to never allow yourself such a cheat. And it has nothing to do with the few calories ingested. The implications are ...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Lifestyle autoimmune blood sugar gluten grains Inflammation joint pain skin rash Weight Loss Source Type: blogs
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