Galvanic Skin Response (GSR)/Electrodermal/Skin Conductance Biofeedback on Epilepsy: A Systematic Review and Meta-Analysis

Conclusion Despite the above limitations, this systematic review supports a view that modulation of sympathetic activity using GSR biofeedback represents a promising new therapeutic tool for management of seizures in patients with epilepsy. For future clinical trials, important elements to be considered include size of patient population, seizure type, double-blinding, inclusion of an appropriate control group, and robust randomization methods. Ethics Statement We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines. Author Contributions YN is a pioneer of GSR biofeedback therapy for epilepsy and provided the systematic overview of historical development of this approach. YN wrote the first draft together with CIJ. CIJ is a medical statistician and was responsible for planning the statistical model and conducting the meta-analysis. AS provided independent oversight and unbiased expertise to the paper. All three authors contributed to the review, interpretation of the analysis, and writing of the paper. Acknowledgments YN's studies were supported by the Bial Foundation and the Wellcome Trust. We thank Profs. Neil Harrison and Hugo Critchley for stimulating discussion and for encouragement to write this systematic review and meta-analysis. Conflict of Interest Statement YN is named as the inventor on a patent for biofeedback treatment of epilepsy. YN ha...
Source: Frontiers in Neurology - Category: Neurology Source Type: research