A case of early myoclonic encephalopathy with intractable seizures successfully treated with high-dose phenobarbital

Early myoclonic encephalopathy (EME) is an epileptic syndrome that develops in neonates, commonly within 1  month of birth. The condition is characterized by irregular, partial, and asynchronous myoclonus. The seizures in EME are generally refractory to antiepileptic drugs and no effective treatment for EME has been established. We encountered a case of EME in which oral high-dose phenobarbital therapy effectively alleviated seizures.
Source: Brain and Development - Category: Neurology Authors: Tags: Case Report Source Type: research