Corticobasal syndrome with visual hallucinations and probable REM-sleep behavior disorder: an autopsied case report of a patient with CBD and LBD pathology.

This report highlights the importance of considering co-existing pathologies when a clinical presentation defies categorization, and demonstrates that salient features of dementia with Lewy bodies may result from pathology limited to the brainstem. PMID: 31006355 [PubMed - as supplied by publisher]
Source: Neurocase - Category: Neurology Authors: Tags: Neurocase Source Type: research

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ConclusionsA history of MST is common among older women veterans and associated with a range of medical and mental health diagnoses. These findings call attention to the need for additional research in this understudied population, and the importance of trauma-informed care approaches for women across the lifespan.
Source: Journal of General Internal Medicine - Category: Internal Medicine Source Type: research
Conditions:   Dementia;   Alzheimer Disease;   Circadian Rhythm Disorders;   Circadian Rhythm Sleep Disorder;   Insomnia;   Hypersomnia;   Cognitive Impairment;   Cognitive Decline;   Mild Cognitive Impairment;   Frontotemporal Dementia;   Neurocognitive Disorders;   Vascular Dementia;   Sleep Disorder;   Memory Impairment Intervention:   Behavioral: Tailored music listening intervention Sponsor:   University of Pennsylvania Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Researchers at Boston University studied 13 people's brains and said the findings were 'striking'. Cerebrospinal fluid (CSF) rushes into the brain every 20 seconds or so and appears to flush out toxins.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
In conclusion, actual knowledge of BPSD/NPS-like symptoms of age-related cognitive deficits in the gray mouse lemur and the recent demonstration of the similarity of these symptoms with those seen in humans offer promising new ways of investigating both the prevention and treatment of pathological aging.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusions: The iterative refinement process was successful in finalizing the intervention program, with evidence of sleep improvements. Formal pilot testing of the program will provide further information on feasibility and effectiveness. IMPLICATIONS FOR REHABILITATION Our dyadic behavioral sleep program can be tailored to various types of sleep problems among patients with Alzheimer's disease and their family caregivers, with the goal of improving daytime function by reducing sleep disturbances at night. Caregiver training and participation of both members of the dyad in sleep management may benefit the patients' sleep...
Source: Disability and Rehabilitation - Category: Rehabilitation Authors: Tags: Disabil Rehabil Source Type: research
AbstractPurpose of ReviewTo evaluate and summarize recent research articles pertaining to insomnia in older adults that can guide healthcare providers on factors to consider when assessing and managing insomnia.Recent FindingsUp to 75% of older adults experience symptoms of insomnia. Insomnia is associated with socioeconomic status, racial and ethnic classification, family relationships, medical and mental health disorders, cognitive function, and dementia. Although one-fifth of older adults are still prescribed sleep medications, cognitive behavioral therapy for insomnia is the first-line treatment for insomnia  and ...
Source: Current Geriatrics Reports - Category: Geriatrics Source Type: research
MONDAY, Oct. 21, 2019 -- Long sleep duration predicts seven-year cognitive decline among U.S. Hispanic/Latino patients, according to a study published online Oct. 9 in Alzheimer's&Dementia. Alberto R. Ramos, M.D., from the University of Miami...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
CONCLUSIONS: ECT is probably the most promising interventional procedure needing further investigation in order to obtain specific protocols and a consensus on indications. Preliminary data on rTMS, tDCS, and VNS are encouraging although randomised controlled trials to investigate and compare their efficacy in the treatment of BPSD are still lacking. Their feasibility profile could represent an important advantage over ECT. DBS could represent a very effective therapy for behavioural disorders, but knowledge of the precise neuroanatomical targets for BPSD is currently too limited to justify this invasive approach. PMI...
Source: Swiss Medical Weekly - Category: General Medicine Authors: Tags: Swiss Med Wkly Source Type: research
DEMENTIA is a progressive neurological condition that can make everyday activities harder for the person affected. Recent research suggests getting a certain amount of sleep can increase a person ’s risk.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 9 October 2019Source: Alzheimer's &DementiaAuthor(s): Alberto R. Ramos, Wassim Tarraf, Benson Wu, Susan Redline, Jianwen Cai, Martha L. Daviglus, Linda Gallo, Yasmin Mossavar-Rahmani, Krista M. Perreira, Phyllis Zee, Donglin Zeng, Hector M. GonzalezAbstractIntroductionTo determine if sleep-disordered breathing (SDB), daytime sleepiness, insomnia, and sleep duration predict seven-year neurocognitive decline in US Hispanics/Latinos (N = 5247).MethodsThe exposures were baseline SDB, daytime sleepiness, insomnia, and sleep duration. The outcomes were change in episodic learning ...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - Category: Geriatrics Source Type: research
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