How to improve patient response to cardiac resynchronization therapy?

I read the study by Strik et al. [1] about the application of activation delay vector (ADV) obtained by electrocardiographic mapping (ECM) to identify the electrical substrate for cardiac resynchronization therapy (CRT) with great interest. However, the authors neglected to discuss important findings that did not support their results and other simpler methods that might improve patient selection for CRT. In contrast to the authors' results based solely on acute response to left ventricular (LV) pacing optimization, echocardiographic latest peak radial strain-guided LV lead placement improved patient outcomes compared with conventional LV pacing in two prospective randomized studies [STARTER [2], TARGET [3]] using hard clinical endpoints.
Source: International Journal of Cardiology - Category: Cardiology Authors: Tags: Letter to the Editor Source Type: research