The Association of Paternal IQ With Autism Spectrum Disorders and its Comorbidities: A Population-Based Cohort Study

We examined the association between paternal intelligence and ASD, considering co-occurring intellectual disability (ID) and attention-deficit hyper-activity disorder (ADHD).
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: New Research Source Type: research

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To examine the association of anemia with autism spectrum disorder (ASD), attention deficit/hyperactivity disorder (ADHD), and learning disability in US children.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Original Articles Source Type: research
Families of children with neurodevelopmental disorders are especially vulnerable during the COVID-19 pandemic. Physical distancing requirements and closure of schools and services in the context of the COVID-19 pandemic are likely challenging to everyone but may be particularly impactful for families with children with neurodevelopmental disorders ([NDDs], eg, intellectual disability, attention-deficit/hyperactivity disorder [ADHD], autism spectrum disorder [ASD]). Although a small number of children may experience less stress or anxiety due to reduced social and academic expectations,1 for many children with NDDs, and par...
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Letter to the Editor Source Type: research
CONCLUSIONS: The risk for major psychiatric disorders was consistently elevated across all types of FDRs of individuals with ASD. FDRs of individuals with ASD-ID are at further higher risk for ASD and schizophrenia. Our results provide leads for future investigation of shared etiologic pathways of ASD, ID and major psychiatric disorders and highlight the importance of mental health care delivered to at-risk families for early diagnoses and interventions. PMID: 32914742 [PubMed - as supplied by publisher]
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Authors: Iasevoli F, Barone A, Buonaguro EF, Vellucci L, de Bartolomeis A Abstract INTRODUCTION: Neurodevelopmental disorders (NDDs) are a group of complex and heterogeneous disorders, caused by the disruption of normal brain development. Antipsychotic agents are frequently used in these disorders to treat maladaptive conduct. However, a systematic evaluation of their safety/tolerability in NDDs is still lacking. Given the unique neurobiology of NDDs, antipsychotics may be expected to elicit distinctive side effects. AREAS COVERED: PubMed was systematically searched for all published studies from 1980 until 202...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
Fragile X syndrome (FXS) is the most common identifiable cause of inherited intellectual disability and autism spectrum conditions, and is associated with a range of physical, cognitive and behavioural characteristics. Alongside intellectual disability, heightened rates of autism spectrum disorder, anxiety disorders, attention-deficit-hyperactivity disorder, self-injury and aggression are reported. Timely identification of FXS as well as assessments of common co-morbid psychological conditions and underlying health problems are essential to ensure individuals with FXS receive appropriate support.
Source: Paediatrics and Child Health - Category: Pediatrics Authors: Tags: Personal practice Source Type: research
The objective of our study was to evaluate the frequency of treatable inborn errors of metabolism (IEM) in a clinical sample of Mexican children and adolescents with neurodevelopmental disorders (NDD). Amino acids and acylcarnitines in blood samples of 51 unrelated children and adolescents were analyzed by tandem mass spectrometry to detect treatable IEM of small molecules. One patient with isovaleric acidemia and autism spectrum disorder (ASD) and another with beta-ketothiolase deficiency and ASD/intellectual disability/attention-deficit/hyperactivity disorder (ADHD) were diagnosed, indicating an IEM frequency of 3.9% (1:...
Source: Journal of Autism and Developmental Disorders - Category: Psychiatry Authors: Tags: J Autism Dev Disord Source Type: research
Women who use cannabis while pregnant have an elevated risk of having children with autism spectrum disorder (ASD), according to astudy published today inNature Medicine.“Children with prenatal cannabis exposure had an increase of 50% in the risk of an autism diagnosis over the study period, and these associations were robust after controlling for confounding,” wrote Daniel Corsi, Ph.D., of the University of Ottawa and colleagues.Corsi and colleagues analyzed the health outcomes of over 500,000 children born in Ontario between April 1, 2007, and March 31, 2012, by linking pregnancy data from Ontario ’s bi...
Source: Psychiatr News - Category: Psychiatry Tags: ADHD attention-deficit/hyperactivity disorder autism spectrum disorder cannabis Daniel Corsi developmental risks substance use Source Type: research
AbstractIn this review, we describe and discuss neurodevelopmental phenotypes arising from rare, high penetrance genomic variants which directly influence synaptic vesicle cycling (SVC disorders). Pathogenic variants in each SVC disorder gene lead to disturbance of at least one SVC sub ‐process, namely vesicle trafficking (for exampleKIF1A andGDI1), clustering (for exampleTRIO,NRXN1 andSYN1), docking and priming (for exampleSTXBP1), fusion (for exampleSYT1 andPRRT2) or re ‐uptake (for exampleDNM1, AP1S2 andTBC1D24). We observe that SVC disorders share a common set of neurological symptoms (movement disorders, epilepsie...
Source: Journal of Neurochemistry - Category: Neuroscience Authors: Tags: REVIEW Source Type: research
Missing social contacts and altered routines, disturbed sleep and eating habits can be particularly intense for the kids with developmental challenges.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Special Education Children and Childhood Education (K-12) Parenting Intellectual Disabilities Coronavirus (2019-nCoV) Quarantines Autism Attention Deficit Hyperactivity Disorder Source Type: news
AbstractDue to lack of previous studies, we aimed at evaluating the use of the Five to Fifteen (FTF) questionnaire in adults with neurodevelopmental disorders (NDD) and in controls without NDD. The NDD group consisted of adults with autism spectrum disorder ASD (n = 183) or attention-deficit/hyperactivity disorder (ADHD) (n = 174) without intellectual disability, recruited from a tertiary outpatient clinic. A web survey was used to collect data from general population adult control group without NDD (n = 738). The participants were retrospectively rated by their parents regarding c...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
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