Semaphorin4A coordinately induces inflammation and fibrosis in systemic sclerosis

ConclusionThis study identifies direct and dual roles for Sema4A in promoting inflammation and fibrosis, two main features of SSc, suggesting that Sema4A might be a novel therapeutic target in SSc.This article is protected by copyright. All rights reserved.

https://onlinelibrary.wiley.com/doi/abs/10.1002/art.40915?af=R

Source: Arthritis and Rheumatology - April 22, 2019 Category: Rheumatology Authors: Tiago Carvalheiro, Alsya J. Affandi, Beatriz Malvar ‐Fernández, Ilse Dullemond, Marta Cossu, Andrea Ottria, Jorre S. Mertens, Barbara Giovannone, Femke Bonte‐Mineur, Marc R. Kok, Wioleta Marut, Kris A. Reedquist, Timothy R. Radstake, Sam Tags: Full Length Source Type: research