Circulating cell-free DNA integrity as a diagnostic and prognostic marker for breast and prostate cancers

ConclusionALU species 115 and 247 levels in serum were elevated in breast and prostate cancer patients compared to their counterpart healthy controls. DNA integrity was higher in prostate cancer patients than the control but in breast cancer patients was lower compared to their controls. In prostate but not in breast cancers, DNA integrity increased with disease severity and higher staging.
Source: Cancer Genetics - Category: Cancer & Oncology Source Type: research