Presidential Address

My dear friends, it is a distinct honor to stand before you as we celebrate the many advances that we have made in our profession, and in our individual careers. I am often asked, as I am sure you have: how is it that we chose our mission, what is it that made it so compelling to answer the calling to help a distinct group of deserving people? And I am always struck by how easy it is to answer this question. I tell them there is no other field in medicine that so dramatically improves health, quality of life, and happiness.
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research

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Contributors : Kristoffer G Rigbolt ; Helene ÆgidiusSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusTo improve the understanding of the complex biological processes underlying the development of non-alcoholic steatohepatitis (NASH), a multi-omics approach combining bulk RNA-sequencing based transcriptomics, quantitative proteomics and single-cell RNA-sequencing was used to characterize tissue biopsies from histologically validated diet-induced obese (DIO) NASH mice compared to chow-fed controls. Bulk RNA-sequencing and proteomics showed a clear distinction between phenotypes and...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
CONCLUSIONS: The present study firstly provided quantitative information for metformin effects on weight in different disease states, including patients with type 2 diabetes mellitus, patients with antipsychotic induced weight gain, patients with obesity. PMID: 32940086 [PubMed - as supplied by publisher]
Source: Expert Review of Clinical Pharmacology - Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research
Publication date: Available online 17 September 2020Source: Journal of Critical CareAuthor(s): Brittany R. Kiracofe, Bruce A. Doepker, Heidi M. Riha, Rachel Wilkinson, Elizabeth Rozycki, Eric Adkins, Amy Lehman, Megan A. Van Berkel
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research
Authors: Hwang S, Ren T, Gao B Abstract Obesity and binge drinking often coexist and work synergistically to promote steatohepatitis; however, the underlying mechanisms remain obscure. In this mini-review, we briefly summarize clinical evidence of the synergistical effect of obesity and heavy drinking on steatohepatitis and discuss the underlying mechanisms obtained from the study of several mouse models. High-fat diet (HFD) feeding and binge ethanol synergistically induced steatohepatitis and fibrosis in mice with significant intrahepatic neutrophil infiltration; such HFD-plus-ethanol treatment markedly up-regulat...
Source: Clinical and molecular hepatology - Category: Gastroenterology Tags: Clin Mol Hepatol Source Type: research
Publication date: Available online 18 September 2020Source: Obesity Research &Clinical PracticeAuthor(s): Giancarlo Condello, Chih-Yen Chen
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Publication date: Available online 18 September 2020Source: Obesity Research &Clinical PracticeAuthor(s): April Prunty, M. Kathleen Clark, Amy Hahn, Stephanie Edmonds, Amy O’Shea
Source: Obesity Research and Clinical Practice - Category: Eating Disorders & Weight Management Source Type: research
Abstract Coronavirus disease 2019 (COVID-19) is a global public health concern that can be classified as mild, moderate, severe, or critical, based on disease severity. Since the identification of critical patients is crucial for developing effective management strategies, we evaluated clinical characteristics, laboratory data, treatment provided, and oxygenation to identify potential predictors of mortality among critical COVID-19 pneumonia patients. We retrospectively utilized data from seven critical patients who were admitted to our hospital during April 2020 and required mechanical ventilation. The primary en...
Source: The Tohoku Journal of Experimental Medicine - Category: Research Authors: Tags: Tohoku J Exp Med Source Type: research
Prolonged sleep deprivation can lead to severe health problems in humans and other animals. But why is sleep so vital to our health? A UCLA-led team of scientists has made a major advance in answering  this question and has shown for the first time that a dramatic change in the purpose of sleep occurs at the age of about 2-and-a-half.Before that age, the brain grows very rapidly. During REM sleep, when vivid dreams occur, the young brain is busy building and strengthening synapses — the structures that connect neurons to one another and allow them to communicate.“Don’t wake babies up during REM sleep...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
FRIDAY, Sept. 18, 2020 -- Adult obesity is increasing, with considerable racial and ethnic disparities, according to new data from the U.S. Centers for Disease Control and Prevention. Data from the 2019 CDC Adult Obesity Prevalence Maps show that...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
CONCLUSIONS For overweight patients undergoing nasopharyngeal surgery, the use of rocuronium with sugammadex had the shortest onset time of neuromuscular relaxation, accelerated the reversion of neuromuscular blockade, effectively reduced the occurrence of PORC, relieved postoperative pain, and maintained hemodynamic stability before extubation. The combination of rocuronium and sugammadex may be the best anesthetic regimen for overweight patients undergoing nasopharyngeal surgery. PMID: 32936790 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
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